Klemastin: Perbedaan antara revisi
Konten dihapus Konten ditambahkan
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'''Klemastin''', juga dikenal sebagai '''meklastin''', adalah antagonis histamin H1 generasi pertama (antihistamin) dengan sifat [[antikolinergik]] (pengeringan) dan efek samping [[sedatif]].<ref>{{cite web |url=https://www.drugbank.ca/drugs/DB00283 |title=Clemastine |website=DrugBank.com}}</ref> Seperti halnya antihistamin generasi pertama lain, ia bersifat sedatif.<ref>{{cite web |url=https://www.pharmacytimes.com/p2p/perspectives-on-second-generation-otc-antihistamines |url-status=dead |archive-url=https://web.archive.org/web/20120501100507/http://www.pharmacytimes.com/p2p/Perspectives-on-Second-Generation-OTC-Antihistamines |archive-date=2012-05-01 |title=Perspectives on Second-Generation OTC Antihistamines |website=Pharmacy Times |date=2012-03-30}}</ref><ref>{{cite journal | vauthors = Krouse JH | title = Allergic rhinitis--current pharmacotherapy | journal = Otolaryngologic Clinics of North America | volume = 41 | issue = 2 | pages = 347–58, vii | date = April 2008 | pmid = 18328373 | doi = 10.1016/j.otc.2007.11.014 }}</ref> Dipatenkan pada tahun 1960, obat ini mulai digunakan secara medis pada tahun 1967.<ref name=Fis2006>{{cite book | vauthors = Fischer J, Ganellin CR |title=Analogue-based Drug Discovery |date=2006 |publisher=John Wiley & Sons |isbn=9783527607495 |page=547 |url=https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA547 |language=en}}</ref>
==Kegunaan dalam medis==
==Efek samping==
==Farmakologi==
==Mekanisme kerja==
==Masyarakat dan budaya==
==Penelitian==
==Referensi==
{{Reflist}}
==Pranala luar==
* [https://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682542.html NIH Medline Plus listing on Clemastine]
* [https://web.archive.org/web/20070310064609/http://jcp.sagepub.com/cgi/content/abstract/36/10/911 The pharmacokinetics and bioavailability of clemastine and phenylpropanolamine in single-component and combination formulations]
[[Category:4-Chlorophenyl compounds]]
[[Category:CYP2D6 inhibitors]]
[[Category:Diphenylmethanol ethers]]
[[Category:H1 receptor antagonists]]
[[Category:Muscarinic antagonists]]
[[Category:Pyrrolidines]]
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