Glukuronosiltransferase: Perbedaan antara revisi
Konten dihapus Konten ditambahkan
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Baris 4:
| accessdate = 2011-05-18
| work = Queen Mary University of London
}}</ref> adalah [[enzim]] [[fasa]] II yang meng[[katalis]] reaksi [[konjugasi]] [[gugus fungsional|gugus]] [[glusuronil]] [[asam glusuronat|''uridine 5'-diphosphoglucuronic acid'']] ke berbagai [[substrat]] [[nukleofilik]] eksogenus dan endogenus
| url = http://jn.nutrition.org/content/137/4/890.full
| title = UGT1A1 Polymorphism Is Associated with Serum Bilirubin Concentrations in a Randomized, Controlled, Fruit and Vegetable Feeding Trial
| accessdate = 2011-06-02
| work = Interdisciplinary Graduate Program in Nutritional Sciences, Department of Epidemiology, University of Washington; Jyh-Lurn Chang, Jeannette Bigler, Yvonne Schwarz, Shuying S. Li, Lin Li, Irena B. King, John D. Potter dan Johanna W. Lampe
}}</ref> [[Substrat]] dapat berupa [[bilirubin]] dan [[estrogen]],<ref>{{en}}{{cite web
| url = http://toxsci.oxfordjournals.org/content/78/1/1.full
| title = Glucuronidation and Susceptibility to Chemical Carcinogenesis
| accessdate = 2011-05-18
| work = Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois; Matthew A. Wallig
}}</ref> khususnya
Manusia dengan tingkat glusuronidasi yang rendah, memiliki risiko [[kanker]] yang lebih tinggi, karena [[senyawa organik|senyawa]] hidrokarbon poliaromatik memerlukan konjugasi [[asam glusuronat]] agar dapat menjadi inaktif.
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