Nefrin: Perbedaan antara revisi
Konten dihapus Konten ditambahkan
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Ekspresi nefrin juga terdapat pada [[membran plasma]], [[vesikel]] [[insulin]], [[sel beta]] dan [[sel MIN-6]]
| url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797869
| accessdate = 2011-06-08
| work = Haartman Institute, Department of Bacteriology and Immunology, University of Helsinki, Centre for Bioanalytical Sciences, Dublin City University, Department of Human Genetics, Leiden University Medical Center, Haartman Institute, Department of Pathology and Experimental Animal Centre, University of Helsinki, Clinical Institute of Pathology, Medical University Vienna; Juuso Juhila, Markus Lassila, Ramon Roozendaal, Eero Lehtonen, Marcel Messing, Brigitte Langer, Dontscho Kerjaschki, J. Sjef Verbeek, dan Harry Holthofer
}}</ref> Kenaikan konsentrasi [[gula darah]] akan meningkatkan ekspresi nefrin pada sel beta dan sel MIN-6 sebelum terjadi [[sekresi]] [[insulin]], serta menginduksi [[endositosis]] nefrin pada [[podosit]]. Ekspresi nefrin menurun pada [[diabetes mellitus#diabetes mellitus tipe 2|diabetes tipe 2]] dan [[nefropati]].<ref>{{en}}{{cite web
| url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797921
| title = Nephrin Is Expressed on the Surface of Insulin Vesicles and Facilitates Glucose-Stimulated Insulin Release
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| work = Diabetes Research Institute, University of Miami L. Miller School of Medicine, Division of Nephrology and Hypertension–Miami Institute of Renal Medicine, Division of Molecular Medicine, University of Miami L. Miller School of Medicine, Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Policlinico San Matteo, Università degli Studi di Pavia, The Rolf Luft Research Center for Diabetes and Endocrinology, Cell Matrix Biology, Karolinska Institutet, Clinical Institute of Pathology, Medical University; Alessia Fornoni, Jongmin Jeon, Javier Varona Santos, Lorenzo Cobianchi, Alexandra Jauregui, Luca Inverardi, Slavena A. Mandic, Christina Bark, Kevin Johnson, George McNamara, Antonello Pileggi, R. Damaris Molano, Jochen Reiser, Karl Tryggvason, Dontscho Kerjaschki, Per-Olof Berggren, Peter Mundel, dan Camillo Ricordi
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▲* {{en}} [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797869 Inducible Nephrin Transgene Expression in Podocytes Rescues Nephrin-Deficient Mice from Perinatal Death]
== Rujukan ==
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