ELMO2
Engulfment and cell motility protein 2 adalah protein yang pada manusia yang disandi oleh gen ELMO2.[4]The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein.[5]
Protein disandi oleh gen yang berinteraksi dengan protein cytokinesis 1. Pada cacing C. elegans, protein berfungsi dalam proses fagositosis sel yang telah mati karena apoptosis dan migrasi sel. Pemotongan alternatif pada berbagai varian transkrip semuanya menyandi protein yang sama.
Referensi
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017670 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration". Cell. 107 (1): 27–41. Oct 2001. doi:10.1016/S0092-8674(01)00520-7. PMID 11595183.
- ^ "Entrez Gene: ELMO2 engulfment and cell motility 2".