Prednison
Prednison adalah obat kortikosteroid yang digunakan untuk mengurangi peradangan dan digunakan untuk kondisi autoimun. Prednison digunakan untuk mengobati gangguan alergi, kondisi kulit, kolitis ulserativa, penyakit Crohn, radang sendi, lupus, psoriasis, asma, penyakit paru obstruktif kronik (PPOK) dan banyak lagi kondisi lainnya.[1]
| tradename = Deltasone, Liquid Pred, Orasone, others | Drugs.com = monograph | MedlinePlus = a601102 | licence_EU = | DailyMedID = Prednisone | licence_US = | pregnancy_AU = A | pregnancy_category = | routes_of_administration = By mouth | ATC_prefix = A07 | ATC_suffix = EA03 | ATC_supplemental = H02AB07
| legal_AU = S4 | legal_CA = | legal_UK = | legal_US = Rx only | legal_status =
| bioavailability = 70% | metabolism = prednisolone (liver) | elimination_half-life = 3 to 4 hours in adults. 1 to 2 hours in children[2] | excretion = Kidney
| CAS_number = 53-03-2
| CAS_number_Ref = 
| PubChem = 5865
| IUPHAR_ligand = 7096
| DrugBank = DB00635
| DrugBank_Ref =
| ChemSpiderID = 5656
| ChemSpiderID_Ref =
| UNII = VB0R961HZT
| UNII_Ref = 
| KEGG = C07370
| KEGG_Ref =
| ChEBI = 8382
| ChEBI_Ref =
| ChEMBL = 635
| synonyms =
| IUPAC_name = 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
| ChEMBL_Ref =
| C=21 | H=26 | O=5
| StdInChI = 1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
| StdInChIKey = XOFYZVNMUHMLCC-ZPOLXVRWSA-N
| StdInChIKey_Ref =
| StdInChI_Ref =
| verifiedrevid = 464213538
| Verifiedfields = changed
| smiles = O=C(CO)[C@@]3(O)CC[C@H]2[C@@H]4CC\C1=C\C(=O)\C=C/[C@]1(C)[C@H]4C(=O)C[C@@]23C
}}
Referensi
- ^ https://www.drugs.com/prednisone.html. "Prednisone Uses, Dosage, Side Effects, Warnings". Drugs.com (dalam bahasa Inggris). Diakses tanggal 2023-06-18.
- ^ Pickup ME (1979). "Clinical pharmacokinetics of prednisone and prednisolone". Clinical Pharmacokinetics. 4 (2): 111–128. doi:10.2165/00003088-197904020-00004. PMID 378499.
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