Flu Spanyol: Perbedaan antara revisi

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{{short description|1918–1920 pandemic of H1N1 influenza A virus}}
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{{Infobox pandemic
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| footer =
| disease = [[Influenza]]
| virus_strain = Galur [[Virus influenza A subtipe H1N1|A/H1N1Pubg]]
| location = Seluruh dunia
| first_reported =
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| recovery_cases =
| suspected_cases = 500 juta (perkiraan){{sfn|Taubenberger|Morens|2006}}
| deaths = 17–100 juta (perkiraan)<ref name="brutal">{{cite web |last1=Hagemann |first1=Hannah |title=The 1918 Flu Pandemic Was Brutal, Killing More Than 50 Million People Worldwide |url=https://www.npr.org/2020/04/02/826358104/the-1918-flu-pandemic-was-brutal-killing-as-many-as-100-million-people-worldwide |website=NPR |accessdate=24 July 2020 |date=2 Apr 2020 |archive-date=2021-01-19 |archive-url=https://web.archive.org/web/20210119213925/https://www.npr.org/2020/04/02/826358104/the-1918-flu-pandemic-was-brutal-killing-as-many-as-100-million-people-worldwide |dead-url=no }}</ref>
| territories =
| total_ili =
| website =
}}
'''Flu Spanyol''', yang juga dikenal dengan '''pandemi flu 1918''', adalah [[pandemi influenza]] yang sangat sangat mematikan yang disebabkan oleh [[virus influenza A subtipe H1N1]]. Virus ini menjangkiti sekitar 500 juta orang (sepertiga dari populasi dunia pada saat itu) dalam empat gelombang berturut-turut dari Februari 1918 hingga April 1920. Korban meninggal biasanya diperkirakan antara 17 juta dan 50 juta jiwa, dan mungkin mencapai 100 juta jiwa, sehingga pandemi ini menjadi salah satu [[daftar epidemi|pandemi paling mematikan]] dalam sejarah umat manusia.<ref name="pmid30202996"/><ref>{{cite news|title=History's deadliest pandemics, from ancient Rome to modern America|url=https://www.washingtonpost.com/graphics/2020/local/retropolis/coronavirus-deadliest-pandemics/|date=7 April 2020|access-date=11 April 2020 |first=Michael S .|last=Rosenwald | name-list-style = vanc |work=Washington Post|url-status=live|url-access=subscription|archive-url= https://web.archive.org/web/20200407204000/https://www.washingtonpost.com/graphics/2020/local/retropolis/coronavirus-deadliest-pandemics/ |archive-date=2020-04-07}}</ref>
 
Pengamatan pertama bagi penyakit berikut kematiannya didokumentasikan di [[Amerika Serikat]] (di [[Fort Riley|Kansas]] dan [[Kota New York]]), [[Brest, Finistère|Prancis]], [[Jerman]], dan [[Britania Raya]]. Untuk menjaga moral, sensor yang diberlakukan selama [[Perang Dunia I]] mengecilkan pelaporan awal. Surat kabar [[kebebasan pers|bebas]] melaporkan dampak epidemi di [[Restorasi (Spanyol)|Spanyol]] yang tidak terdampak, seperti penyakit parah [[Alfonso XIII dari Spanyol|Alfonso XIII]] dan cerita-cerita ini seolah mengesankan bahwasanya Spanyol sangat terdampak oleh epidemi. Oleh karenanya, penyakit ini dinamakan flu "Spanyol". Data sejarah dan [[epidemiologi]] tidak memadai untuk mengidentifikasi dengan pasti asal geografi pandemi, dengan pandangan yang beragam mengenai wilayah.
 
Kebanyakan wabah influenza menewaskan merekapenduduk yang sangatusia muda dan sangatusia tua dengan perbandingan yang tidak berimbang, dengan tingkat kelangsungan hidup yang lebih tinggi bagi mereka yang berada di antaranya, tetapi pandemi flu Spanyol mengakibatkan tingkat kematian yang lebih tinggi dari perkiraan bagi remaja.<ref>{{cite journal | vauthors = Gagnon A, Miller MS, Hallman SA, Bourbeau R, Herring DA, Earn DJ, Madrenas J | title = Age-specific mortality during the 1918 influenza pandemic: unravelling the mystery of high young adult mortality | journal = PLOS ONE | volume = 8 | issue = 8 | pages = e69586 | year = 2013 | pmid = 23940526 | pmc = 3734171 | doi = 10.1371/journal.pone.0069586 | bibcode = 2013PLoSO...869586G | doi-access = free }}</ref> Ilmuwan menawarkan beberapa penjelasan yang mungkin bagi tingkat kematian yang tinggi semasa pandemi. Beberapa analisis menunjukkan virus itu sangat mematikan karena memicu [[badai sitokin]] yang merusak [[sistem imun]] yang lebih kuat pada remaja.{{sfn|Barry|2004b}} Analisis yang berlawanan pada 2007 dari jurnal kedokteran dari zaman pandemi menemukan bahwa [[infeksi virus]] tidak lebih agresif daripada galur [[influenza]] lainnya.<ref>{{cite journal | vauthors = MacCallum WG |year=1919 |title=Pathology of the pneumonia following influenza |url=https://zenodo.org/record/1423419 |journal=JAMA: The Journal of the American Medical Association |volume=72 |issue=10 |pages=720–23 |doi=10.1001/jama.1919.02610100028012 |access-date=16 August 2019 |archive-url=https://web.archive.org/web/20200125210346/https://zenodo.org/record/1423419 |archive-date=25 January 2020 |url-status=live }}</ref><ref>{{Cite journal |last1=Hirsch |first1=Edwin F. |first2=Marion |last2=McKinney | name-list-style = vanc |year=1919 |title=An epidemic of pneumococcus broncho-pneumonia |journal=Journal of Infectious Diseases |volume=24 |issue=6 |pages=594–617 |doi=10.1093/infdis/24.6.594 |jstor= 30080493 |url=https://zenodo.org/record/1431769 |access-date=2020-11-13 |archive-date=2020-07-24 |archive-url=https://web.archive.org/web/20200724111322/https://zenodo.org/record/1431769 |dead-url=no }}</ref> Sebaliknya, [[malagizi]], kamp medis dan rumah sakit yang penuh, serta [[higienis|higienitas]] yang buruk, diperparah pula oleh perang pada saat itu, mendorong [[superinfeksi]] bakteri. Superinfeksi ini menewaskan sebagian besar korban.<ref>{{cite journal | vauthors = Brundage JF, Shanks GD | title = What really happened during the 1918 influenza pandemic? The importance of bacterial secondary infections | journal = The Journal of Infectious Diseases | volume = 196 | issue = 11 | pages = 1717–18; author reply 1718–19 | date = December 2007 | pmid = 18008258 | doi = 10.1086/522355 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Morens DM, Fauci AS | title = The 1918 influenza pandemic: insights for the 21st century | journal = The Journal of Infectious Diseases | volume = 195 | issue = 7 | pages = 1018–28 | date = April 2007 | pmid = 17330793 | doi = 10.1086/511989 | doi-access = free }}</ref>
 
Flu Spanyol 1918 adalah pandemi pertama dari dua pandemi yang disebabkan oleh virus influenza A H1N1, manakala pandemi kedua adalah [[pandemi flu babi 2009]].<ref>{{cite web |url=http://www.pasteur.fr/infosci/conf/CRC/Grippe_CRC.ppt |title=La Grippe Espagnole de 1918 |format=Powerpoint |language=fr |publisher=[[Institut Pasteur]] |url-status=dead |archive-url=https://web.archive.org/web/20151117020243/http://www.pasteur.fr/infosci/conf/CRC/Grippe_CRC.ppt |archive-date=17 November 2015 }} (also [https://www.powershow.com/view/2a8245-ODY3M/Grippe_espagnole_de_1918_consquences_dmographiques_long_terme_powerpoint_ppt_presentation# here] {{Webarchive|url=https://web.archive.org/web/20200417064626/https://www.powershow.com/view/2a8245-ODY3M/Grippe_espagnole_de_1918_consquences_dmographiques_long_terme_powerpoint_ppt_presentation |date=2020-04-17 }}, requires Flash player)</ref>
 
== Etimologi ==
Meskipun asal geografinya tidak diketahui, penyakit ini disebut flu Spanyol sejak gelombang pertama pandemi.<ref name="resurgence">{{Cite web |author=Dave Roos |date=3 March 2020 |url=https://www.history.com/news/spanish-flu-second-wave-resurgence |title=Why the Second Wave of the 1918 Spanish Flu Was So Deadly |publisher=[[History.com]] |accessdate=23 July 2020 |archive-date=2020-07-30 |archive-url=https://web.archive.org/web/20200730014432/https://www.history.com/news/spanish-flu-second-wave-resurgence |dead-url=no }}</ref>{{sfn|Porras-Gallo|Davis|2014|page=51}}{{sfn|Galvin|2007}} Spanyol tidak terlibat dalam Perang Dunia I dan tetap netral. Pada saat yang sama, [[penyensoran]] pada masa perang juga tidak diberlakukan di sana.<ref>{{cite news |archive-url=https://web.archive.org/web/20100127100727/http://www.channel4.com/news/articles/world/spanish%20flu%20facts/111285 |archive-date=27 January 2010 |url=http://www.channel4.com/news/articles/world/spanish%20flu%20facts/111285 |website=Channel&nbsp;4 News |title=Spanish flu facts}}</ref><ref>{{cite web |last=Anderson |first=Susan | name-list-style = vanc |title=Analysis of Spanish flu cases in 1918–1920 suggests transfusions might help in bird flu pandemic |url=http://www.eurekalert.org/pub_releases/2006-08/acop-aos082806.php |publisher=[[American College of Physicians]] |access-date=2 October 2011 |date=29 August 2006 |archive-url=https://web.archive.org/web/20111125222223/http://www.eurekalert.org/pub_releases/2006-08/acop-aos082806.php |archive-date=25 November 2011 |url-status=live }}</ref> Oleh karena itu, surat kabar [[kebebasan pers|bebas]] melaporkan dampak epidemi, seperti penyakit parah Raja [[Alfonso XIII dari Spanyol]] dan cerita yang tersebar luas ini seolah mengesankan bahwasanya Spanyol sangat terdampak oleh pandemi ini.{{sfn|Barry|2004|p=171}}
 
Nama lain juga digunakan semasa pandemi. Mirip dengan nama flu Spanyol, banyak di antaranya juga menyinggung asal mula penyakit tersebut. Di [[Senegal]], penyakit ini dinamakan 'flu Brasil' dan di [[Brasil]], penyakit ini dinamakan 'flu Jerman', manakala di [[Polandia]], penyakit ini dikenal dengan 'penyakit Bolshevik'.{{sfn|Spinney|2018|p=58}} Di Spanyol sendiri, "Tentara Napoli" digunakan untuk menjuluki flu ini, setelah salah satu penulis [[libreto]] menyindir bahwa nomor musik paling populer dari sandiwara itu, ''Tentara Napoli'', sama menariknya dengan flu; Tentara Napoli sendiri ber[unca dari operet tahun 1916 berjudul ''The Song of Forgetting'' (La canción del olvido).{{sfn|Davis|2013|pp=103–36}} Kini, 'flu Spanyol' (Gripe Española) adalah nama yang paling banyak digunakan bagi pandemi ini di Spanyol.<ref>{{cite web |last=Landgrebe |first=Phillip |title=100 Years After: The Name of Death |url=https://historycampus.org/2018/spanish-flu-100-years-after-name-of-the-death/ |publisher=[[historycampus.org]] |access-date=16 August 2020 |date=29 December 2018 |archive-url=https://web.archive.org/web/20200816202544/https://historycampus.org/2018/spanish-flu-100-years-after-name-of-the-death/ |archive-date=16 August 2020 |url-status=live }}</ref>
 
Istilah lain bagi virus ini di antaranya "pandemi influenza 1918", "pandemi flu 1918", atau variasi dari kedua istilah itu.<ref>{{Cite web|url=https://www.who.int/influenza/pandemic-influenza-an-evolving-challenge/en/|title=Pandemic influenza: an evolving challenge | date=22 May 2018|website=World Health Organization|url-status=live|archive-url=https://web.archive.org/web/20200320220124/https://www.who.int/influenza/pandemic-influenza-an-evolving-challenge/en/|archive-date=20 March 2020|access-date=20 March 2020}}</ref><ref>{{Cite web|url=https://www.britannica.com/event/influenza-pandemic-of-1918-1919|title=Influenza pandemic of 1918–19 | date=4 March 2020|website=[[Encyclopaedia Britannica]]|url-status=live|archive-url=https://web.archive.org/web/20200320220920/https://www.britannica.com/event/influenza-pandemic-of-1918-1919|archive-date=20 March 2020|access-date=20 March 2020}}</ref><ref>{{Cite news|last=Chodosh|first=Sara | name-list-style = vanc |url=https://www.popsci.com/story/health/coronavirus-1918-flu-pandemic/|title=What the 1918 flu pandemic can teach us about COVID-19, in four charts|date=18 March 2020|work=PopSci|access-date=20 March 2020|archive-date=2020-12-24|archive-url=https://web.archive.org/web/20201224025632/https://www.popsci.com/story/health/coronavirus-1918-flu-pandemic/|dead-url=no}}</ref>
 
== Sejarah ==
=== Garis waktu ===
==== Gelombang pertama: awal 1918 ====
Pandemi ini pertama kali dimulai pada 4 Maret 1918 lewat kasus bernama Albert Gitchell, seorang juru masak tentara di [[Camp Funston]], [[Kansas]], United States, meskipun terdapat kemungkinan adanya kasus sebelum dirinya.<ref name=":3">{{Cite book|last=Spinney |first=Laura |title=Pale rider: the Spanish flu of 1918 and how it changed the world |date=2018 |publisher=Vintage |isbn=978-1-78470-240-3 |location= |oclc=1090305029 |page=36}}</ref> Penyakit ini telah diamati di [[Haskell, Kansas|Haskell]] pada Januari 1918 dan mendorong dokter setempat Loring Miner untuk memperingati jurnal akademik [[Dinas Kesehatan Masyarakat Amerika Serikat]].<ref>{{Cite journal|last=Barry|first=John M|date=2004-01-20|title=The site of origin of the 1918 influenza pandemic and its public health implications|journal=Journal of Translational Medicine|volume=2|issue=1|page=3|doi=10.1186/1479-5876-2-3|issn=1479-5876|pmid=14733617|pmc=340389}}</ref> Dalam beberapa hari, 522 pria di kamp dilaporkan sakit.<ref>{{cite web|title=1918 Flu (Spanish flu epidemic)|url=http://www.avian-bird-flu.info/spanishfluepidemic1918.html|archive-url=https://web.archive.org/web/20080521071645/http://www.avian-bird-flu.info/spanishfluepidemic1918.html|archive-date=21 May 2008|website=Avian Bird Flu}}</ref> Pada 11 Maret 1918, virus telah mencapai [[Queens]], [[New York]].<ref>{{Cite web|last=Sheidlower|first=Noah|date=2020-03-17|title=How NYC Survived the 1918 Spanish Flu Pandemic|url=https://untappedcities.com/2020/03/17/how-nyc-survived-the-1918-spanish-flu-pandemic/|access-date=2020-10-08|website=Untapped New York|language=en-US|archive-date=2020-09-29|archive-url=https://web.archive.org/web/20200929134901/https://untappedcities.com/2020/03/17/how-nyc-survived-the-1918-spanish-flu-pandemic/|dead-url=no}}</ref> Kegagalan mengambil tindakan pencegahan pada bulan Maret atau April kemudian mendapat kritik.{{sfn|Billings|1997}}
 
Karena Amerika Serikat bergabung dalam [[Perang Dunia I]], penyakit ini menyebar dengan sangat cepat dari Kamp Funston, tempat pelatihan utama bagi [[Pasukan Ekspedisi Amerika]], ke kamp-kamp [[Angkatan Darat Amerika Serikat]] lainnya dan Eropa, sehingga menjadi epidemi di kawasan [[Amerika Serikat Barat Tengah|Barat Tengah]], [[Pantai Timur Amerika Serikat|Pantai Timur]], dan pelabuhan di Prancis pada April 1918, serta mencapai [[Front Barat (Perang Dunia I)|Perang Dunia]] pada pertengahan April.<ref name=":3" /> Penyakit ini kemudian menyebar dengan sangat cepat ke wilayah Prancis lainnya, Britania Raya, Italia, dan Spanyol, serta mencapai [[Wrocław|Breslau]] dan [[Odessa]] pada bulan Mei. Setelah menandatangani [[Perjanjian Brest-Litovsk]] (Maret 1918), Jerman mulai membebaskan tawanan perang Rusia, yang kemudian membawa penyakit itu ke tanah airnya.<ref>{{Cite journal|last=|first=|date=2011|title=The Memoirs of Herbert Hoover: Years of Adventure, 1874–1920. (New York: Macmillan Company. 1951. pp. xi, 496.) and Herbert Hoover and the Russian Prisoners of World War I: A Study in Diplomacy and Relief, 1918–1919. By Edward F. Willis. (Stanford: Stanford University Press. 1951. pp. viii, 67.)|journal=The American Historical Review|volume=|pages=12|doi=10.1086/ahr/57.3.709|issn=1937-5239}}</ref> Penyakit ini mencapai Afrika Utara, India, dan Jepang pada bulan Mei, serta setelah itu kemungkinan besar menyebar ke seluruh dunia seperti kasus yang dilaporkan di Asia Tenggara pada bulan April.<ref name=":4">{{Cite book|last=Spinney |first=Laura |title=Pale rider: the Spanish flu of 1918 and how it changed the world |date=2018 |publisher=Vintage |isbn=978-1-78470-240-3 |location= |oclc=1090305029 |page=37}}</ref> Pada bulan Juni, wabah dilaporkan di Tiongkok.<ref>{{Cite news |date=1918-06-01 |title=Queer Epidemic Sweeps North China; Banks and Silk Stores in Peking Closed – Another Loan Sought from Japan. |language=en-US |work=[[The New York Times]] |url=https://www.nytimes.com/1918/06/01/archives/queer-epidemic-sweeps-north-china-banks-and-silk-stores-in-peking.html |access-date=2020-06-22 |issn=0362-4331 |df=mdy-all |archive-date=2020-06-24 |archive-url=https://web.archive.org/web/20200624031144/https://www.nytimes.com/1918/06/01/archives/queer-epidemic-sweeps-north-china-banks-and-silk-stores-in-peking.html |dead-url=no }}</ref> Setelah mencapai Australia pada bulan Juli, gelombang pertama mulai melandai.
 
Gelombang pertama flu berlangsung dari triwulan pertama 1918 dan cenderung ringan.<ref name="BHM1991">{{cite journal |last1=Patterson |first1=K. David |last2=Pyle |first2=Gerald F. |title=The Geography and Mortality of the 1918 Influenza Pandemic |url=https://archive.org/details/sim_bulletin-of-the-history-of-medicine_spring-1991_65_1/page/4 |journal=Bulletin of the History of Medicine |date=1991 |volume=65 |issue=1 |pages=4–21 |pmid=2021692 |jstor=44447656 }}</ref> Tingkat kematian tidak terlalu jauh di atas biasanya;<ref name="NIH1918Influenza">{{cite journal |last1=Taubenberger |first1=Jeffery K. |last2=Morens |first2=David M. |title=1918 Influenza: the Mother of All Pandemics |journal=Emerging Infectious Diseases |date=2006 |volume=12 |issue=1 |pages=15–22 |doi=10.3201/eid1201.050979 |pmid=16494711 |pmc=3291398 }}</ref> sekira 75 ribu kematian yang berkaitan dengan flu dilaporkan pada enam bulan pertama tahun 1918 di Amerika Serikat, dibandingkan dengan sekira 63 ribu kematian selama tempo waktu yang sama pada 1915.<ref name="CDCMortality1918">{{cite web |url=https://www.cdc.gov/nchs/data/vsushistorical/mortstatsh_1918.pdf |title=Mortality Statistics 1918: Nineteenth Annual Report |publisher=[[United States Census Bureau]] |page=28 |date=1920 |accessdate=29 May 2020 |archive-date=2020-07-11 |archive-url=https://web.archive.org/web/20200711052046/https://www.cdc.gov/nchs/data/vsushistorical/mortstatsh_1918.pdf |dead-url=no }}</ref> Kurang dari seribu orang meninggal karena influenza antara Mei dan Juni 1918 di Madrid, Spanyol.<ref name="NIHInfluenza2010">{{cite journal |last1=Erkoreka |first1=Anton |title=The Spanish influenza pandemic in occidental Europe (1918–1920) and victim age |journal=Influenza and Other Respiratory Viruses |date=2010 |volume=4 |issue=2 |pages=81–89 |doi=10.1111/j.1750-2659.2009.00125.x |pmid=20167048 |pmc=5779284 }}</ref> Tiada karantina yang dilaporkan selama triwulan pertama 1918. Namun, gelombang pertama menyebabkan gangguan yang signifikan dalam operasi militer Perang Dunia I, dengan tiga perempat tentara Prancis, setengan pasukan Inggris, dan lebih dari 900,000 tentara Jerman menderita penyakit ini.<ref name=":5">{{Cite book|last=Spinney, Laura.|title=Pale rider : the Spanish flu of 1918 and how it changed the world|date=2018|publisher=Vintage|isbn=978-1-78470-240-3|location=|pages=38|oclc=1090305029}}</ref>
 
==== Gelombang kedua: akhir 1918 ====
[[File:Spanish flu in 1918, Police officers in masks, Seattle Police Department detail, from- 165-WW-269B-25-police-l (cropped).jpg|thumb|Seattle police wearing masks in December 1918]]
Gelombang kedua bermula pada pertengahan akhir Agustus, mungkin menyebar ke [[Boston]] dan [[Freetown]], [[Koloni dan Protektorat Sierra Leone|Sierra Leone]], dengan kapal dari [[Brest, Finistère|Brest]], tempat gelombang itu kemungkinan besar tiba dengan pasukan Amerika Serikat atau rekrutan Prancis bagi pelatihan angkatan laut.<ref name=":5" /> Dari [[Boston Navy Yard]] dan Camp Devens (kemudian berganti nama menjadi [[Fort Devens]]), sekitar 30 mil barat Boston, situs militer Amerika Serikat lainnya segera terdampak, begitu pula pasukan yang diangkut ke Eropa.<ref>{{cite journal|vauthors=Byerly CR|date=April 2010|title=The U.S. military and the influenza pandemic of 1918–1919|journal=Public Health Reports|volume=125 Suppl 3|issue=|pages=82–91|doi=|pmc=2862337|pmid=20568570}}</ref> Pergerakan pasukan membuat penyakit ini menyebar selama dua bulan ke depan ke seluruh Amerika Utara, dan kemudian ke Amerika Tengah dan Amerika Selatan, juga mencapai Brasil dan Karibia lewat kapal..<ref name=":6">{{Cite book|last=Spinney, Laura.|title=Pale rider : the Spanish flu of 1918 and how it changed the world|date=2018|publisher=Vintage|isbn=978-1-78470-240-3|location=|pages=39|oclc=1090305029}}</ref> Pada Juli 1918, penyakit ini menjangkiti beberapa tentara [[Kekaisaran Utsmaniyah]].<ref name=":0">{{Cite web|title=Atatürk işgalcilerden önce İspanyol Gribini yenmişti|url=https://www.sozcu.com.tr/2020/yazarlar/sinan-meydan/ataturk-isgalcilerden-once-ispanyol-gribini-yenmisti-5767483/|access-date=2020-11-02|website=www.sozcu.com.tr|language=tr|archive-date=2020-11-08|archive-url=https://web.archive.org/web/20201108004306/https://www.sozcu.com.tr/2020/yazarlar/sinan-meydan/ataturk-isgalcilerden-once-ispanyol-gribini-yenmisti-5767483/|dead-url=no}}</ref> Dari Freetown, pandemi terus menyebar melalui Afrika Barat di sepanjang pantai, sungai, dan rel kereta api kolonia, serta dari rel kereta api ke masyarakat yang lebih terpencil, sementara penyakit tersebut menyebar ke Afrika Selatan pada bulan September lewat kapal yang membawa kembali anggota [[Korps Buruh Pribumi Afrika Selatan]] yang kembali dari Prancis.<ref name=":6" /> Dari situ, penyakit ini menyebar ke seluruh bagian selatan Aftika dan di luar [[Zambezi]]. Penyakit ini mencapai [[Etiopia]] pada bulan November.<ref>{{Cite book|last=Spinney, Laura.|title=Pale rider : the Spanish flu of 1918 and how it changed the world|date=2018|publisher=Vintage|isbn=978-1-78470-240-3|location=|pages=40|oclc=1090305029}}</ref> On September 15, New York City saw its first fatality from influenza.<ref>{{Cite book|last=Barry|first=John M.|title=The Great Influenza|url=https://archive.org/details/greatinfluenzaep00barr|publisher=Penguin Books|year=2005|isbn=0670894737|location=United States|pages=[https://archive.org/details/greatinfluenzaep00barr/page/270 270]|quote=On September 15, New York City's first influenza death occurred.}}</ref> Pada 15 November, kematian pertama akibat influenza dilaporkan di [[Kota New York]].<ref>{{Cite book|last=Barry|first=John M.|title=The Great Influenza|publisher=Penguin Books|year=2005|isbn=0670894737|location=United States|pages=270|quote=On September 15, New York City's first influenza death occurred.}}</ref> Philadelphia Liberty Loans Parade yang diselenggarakan pada 28 September 1918 untuk memperomosikan [[obligasi kebebasan|obligasi pemerintah]] bagi Perang Dunia I mengakibatkan 12 ribu kasus kematian setelah wabah penyakit besar menyebar di antara orang-orang yang menghampiri parade.<ref name="philadelphia">{{Cite news|first=Meagan|last=Flynn|url=https://www.washingtonpost.com/nation/2020/03/12/pandemic-parade-flu-coronavirus/|title=What happens if parades aren't canceled during pandemics? Philadelphia found out in 1918, with disastrous results.|date=12 March 2020|work=Washington Post|accessdate=9 July 2020|archive-date=2020-07-04|archive-url=https://web.archive.org/web/20200704064124/https://www.washingtonpost.com/nation/2020/03/12/pandemic-parade-flu-coronavirus/|dead-url=no}}</ref>
 
[[File:USCampHospital45InfluenzaWard.jpg|thumb|[[American Expeditionary Force]] victims of the Spanish flu at U.S. Army Camp Hospital no. 45 in [[Aix-les-Bains]], France, in 1918]]
Dari Eropa, penyakit ini menyebar hingga Rusia, dibawa ke [[Arkhangelsk]] oleh [[campur tangan Rusia Utara]], serta kemudian menyebar ke seluruh Asia setelah [[Perang Saudara Rusia]] dan [[jalur kereta api Trans-Siberia]], mencapai Iran (penyakit ini menyebar melalui kota suci [[Masyhad]]), berikut India pada bulan September, kemudian Cina dan Jepang pada bulan Oktober.<ref>{{Cite book|last=Spinney, Laura.|title=Pale rider : the Spanish flu of 1918 and how it changed the world|date=2018|publisher=Vintage|isbn=978-1-78470-240-3|location=|pages=41|oclc=1090305029}}</ref> Perayaan [[gencatan senjata 11 November 1918]] juga menyebabkan wabah di [[Lima]] dan [[Nairobi]], tetapi pada bulan Desember gelombang kedua sebagian besar telah berakhir.<ref name=":7">{{Cite book|last=Spinney, Laura.|title=Pale rider : the Spanish flu of 1918 and how it changed the world|date=2018|publisher=Vintage|isbn=978-1-78470-240-3|location=|page=42|oclc=1090305029}}</ref>
 
Gelombang kedua pandemi 1918 lebih mematikan daripada gelombang pertama. Gelombang pertama menyerupai wabah flu biasa ketika yang paling berisiko adalah pesakit dan orang lanjut usia, manakala orang yang lebih muda dan sehat dapat pulih dengan mudah. Oktober 1918 adalah bulan dengan tingkat kematian tertinggi dari seluruh pandemi.<ref>{{Cite episode |title=Influenza 1918 |episode-link=List of American Experience episodes#Season 10 (1997–98) |url= https://www.pbs.org/wgbh/americanexperience/films/influenza/|access-date= |series=American Experience |series-link=American Experience |first=Robert |last=Kenner |network=[[Public Broadcasting System|PBS]] |station=[[WGBH-TV|WGBH]] |date= 18 January 2010|season=10 |series-no= |number=5 |minutes= |time= |transcript=Transcript |transcript-url=https://www.pbs.org/wgbh/americanexperience/films/influenza/#transcript |quote= |language=}}</ref> Di Amerika Serikat, sekira 292 ribu kasus kematian dilaporkan antara September –December 1918, dibandingkan dengan sekira 26 ribu kasus kematian selama tempo waktu yang sama pada tahun 1915.<ref name="CDCMortality1918" /> Belanda melaporkan lebih dari 40 ribu kasus kematian karena influenza dan penyakit pernapasan akut.<ref name="EpidemicInfluenza">{{cite web |url=https://quod.lib.umich.edu/f/flu/8580flu.0016.858/47/--epidemic-influenza-a-survey?page=root;rgn=full+text;size=200;view=image |title=Epidemic Influenza |accessdate=4 July 2020 |page=93 |archive-date=2020-07-04 |archive-url=https://web.archive.org/web/20200704055957/https://quod.lib.umich.edu/f/flu/8580flu.0016.858/47/--epidemic-influenza-a-survey?page=root;rgn=full+text;size=200;view=image |dead-url=no }}</ref> [[Pandemi Flu 1918 di India]] adalah yang paling mematikan, dengan estimasi 12,5-20 juta kematian dilaporkan pada kuartal akhir 1918.<ref name="BHM1991" />
 
== Referensi ==
Baris 75 ⟶ 78:
 
== Daftar pustaka ==
* {{cite book|last=Barry|first=John M.|coauthors=|authorlink=|title=The Great Influenza: The Epic Story of the Greatest Plague in History|url=https://archive.org/details/greatinfluenzaep00john|edition=|publisher=Viking Penguin|location=|year=2004|isbn=0-670-89473-7|series=}}
* {{cite book|last=Crosby|first=Alfred W.|coauthors=|authorlink=|title=America's Forgotten Pandemic: The Influenza of 1918|edition=|publisher=Cambridge University Press|location=Cambridge|year=1990|isbn=0-521-38695-0|series=}}
* {{cite book|last=Johnson|first=Niall|coauthors=|authorlink=|title=Britain and the 1918-19 Influenza Pandemic: A Dark Epilogue|edition=|publisher=Routledge|location=London and New York|year=2006|isbn=0-415-36560-0|series=}}
* {{cite journal|last=Johnson|first=Niall|coauthors=|year=2003|title=Measuring a pandemic: Mortality, demography and geography|url=|journal=Popolazione e Storia|pages=31-52}}
* {{cite journal|last=Johnson|first=Niall|coauthors=|year=2003|title=Scottish ’flu – The Scottish mortality experience of the “Spanish flu|url=|journal=Scottish Historical Review|volume=83|issue=2|pages=216-226}}
* {{cite journal|last=Johnson|first=Niall|coauthors=Juergen Mueller|year=2002|title=Updating the accounts: global mortality of the 1918–1920 ‘Spanish’ influenza pandemic|url=https://archive.org/details/sim_bulletin-of-the-history-of-medicine_spring-2002_76_1/page/105|journal=Bulletin of the History of Medicine|issn=|volume=76|pages=105–15}}
* Mendes, Shawn (1998). The Great Pandemic of The Greatest Plague in History
* Kolata, Gina. Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It (1999) ISBN 0-374-15706-5
* {{cite book|last=Little|first=Jean|coauthors=|authorlink=Jean Little|title=If I Die Before I Wake: The Flu Epidemic Diary of Fiona Macgregor, Toronto, Ontario, 1918|url=https://archive.org/details/ifidiebeforeiwak0000litt|edition=|publisher=Scholastic Canada|location=Markham, Ont.|year=2007|isbn=9780439988377|series=[[Dear Canada]]}}
* {{cite journal|last=Noymer|first=Andrew|coauthors=Michel Garenne|year=2000|title=The 1918 Influenza Epidemic's Effects on Sex Differentials in Mortality in the United States|url=https://archive.org/details/sim_population-and-development-review_2000-09_26_3/page/565|journal=Population and Development Review|issn=0098-7921|volume=26|issue=3|pages=565-581|doi=}}
* {{cite journal |author=Oxford JS, Sefton A, Jackson R, Innes W, Daniels RS, Johnson NP |title=World War I may have allowed the emergence of "Spanish" influenza |journal=The Lancet infectious diseases |volume=2 |issue=2 |pages=111-4 |year=2002 |pmid=11901642}}
* {{cite journal |author=Oxford JS, Sefton A, Jackson R, Johnson NP, Daniels RS |title=Who's that lady? |journal=Nat. Med. |volume=5 |issue=12 |pages=1351-2 |year=1999 |pmid=10581070 |doi=10.1038/70913}}
Baris 90 ⟶ 93:
* {{cite journal|last=Rice|first=Geoffrey W.|coauthors=Edwina Palmer|year=1993|title=Pandemic Influenza in Japan, 1918-1919: Mortality Patterns and Official Responses|url=|journal=Journal of Japanese Studies|issn=0095-6848|volume=19|issue=2|pages=389-420|doi=}}
* {{cite book|last=Rice|first=Geoffrey W.|coauthors=|authorlink=|title=Black November: the 1918 Influenza Pandemic in New Zealand|edition=|publisher=|location=Canterbury University Press|year=2005|isbn=1-877257-35-4|series=}}
* {{cite journal |author=Tumpey TM, García-Sastre A, Mikulasova A, ''et al'' |title=Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue=21 |pages=13849-54 |year=2002 |pmid=12368467 |doi=10.1073/pnas.212519699 | url=http://www.pnas.org/cgi/content/full/99/21/13849 |access-date=2007-12-30 |archive-date=2008-05-02 |archive-url=https://web.archive.org/web/20080502062330/http://www.pnas.org/cgi/content/full/99/21/13849 |dead-url=no }}
 
== Lihat pula ==
* [[Flu Spanyol di Indonesia]]
 
== Pranala luar ==
{{commonscat|Spanish flu}}
* [http://www.scribemedia.org/2006/11/22/avian-flu/ Video from Expert Panel Discussion on Avian Flu] {{Webarchive|url=https://web.archive.org/web/20071213060421/http://www.scribemedia.org/2006/11/22/avian-flu/ |date=2007-12-13 }}
* [http://www.nature.com/nature/focus/1918flu/index.html ''Nature'' "Web Focus" on 1918 flu, including new research] {{Webarchive|url=https://web.archive.org/web/20170713115050/http://www.nature.com/nature/focus/1918flu/index.html |date=2017-07-13 }}
* [http://www.stanford.edu/group/virus/uda/ Influenza Pandemic on stanford.edu] {{Webarchive|url=https://web.archive.org/web/20221012023812/https://stanford.edu/group/virus/uda/ |date=2022-10-12 }}
* [[n:The Deadliest Fall|Article: The Deadliest Fall]]
* [http://www.pbs.org/wgbh/amex/influenza/ Influenza 1918 in the United States on pbs.org] {{Webarchive|url=https://web.archive.org/web/20091203114338/http://www.pbs.org/wgbh/amex/influenza/ |date=2009-12-03 }}
* [http://www.pbs.org/wnet/secrets/case_killerflu/index.html Secrets of the Dead: Killer Flu (PBS)] {{Webarchive|url=https://web.archive.org/web/20071212142635/http://www.pbs.org/wnet/secrets/case_killerflu/index.html |date=2007-12-12 }}
* [http://www.upenn.edu/gazette/1198/lynch.html Flu by Eileen A. Lynch. The devastating effect of the Spanish flu in the city of Philadelphia, PA, USA] {{Webarchive|url=https://web.archive.org/web/20050304055539/http://www.upenn.edu/gazette/1198/lynch.html |date=2005-03-04 }}
* [http://www.ninthday.com/tauben.htm Dialog: An Interview with Dr. Jeffery Taubenberger on Reconstructing the Spanish Flu] {{Webarchive|url=https://web.archive.org/web/20230525112536/https://www.ninthday.com/tauben.htm |date=2023-05-25 }}
* [http://www.archives.gov/exhibits/influenza-epidemic/ The Deadly Virus - The Influenza Epidemic of 1918] {{Webarchive|url=https://web.archive.org/web/20230625132132/https://www.archives.gov/exhibits/influenza-epidemic/ |date=2023-06-25 }}, by the National Archives and Records Administration (see actual pictures and records of the time).
* [http://www.nzhistory.net.nz/culture/1003 The 1918 Influenza Pandemic in New Zealand - includes recorded recollections of people who lived through it] {{Webarchive|url=https://web.archive.org/web/20120117175541/http://www.nzhistory.net.nz/culture/1003 |date=2012-01-17 }}
* [http://www.nytimes.com/2005/10/06/health/06flu.html?ex=1286251200&en=3f9a510cfd4c3d45&ei=5090 Experts Unlock Clues to Spread of 1918 Flu Virus] {{Webarchive|url=https://web.archive.org/web/20131026111831/http://www.nytimes.com/2005/10/06/health/06flu.html?ex=1286251200&en=3f9a510cfd4c3d45&ei=5090 |date=2013-10-26 }} - ''[[The New York Times]]''
* [http://www.pbs.org/wgbh/amex/influenza/sfeature/latest.html PBS - recovery of flu samples from Alaskan flu victims] {{Webarchive|url=https://web.archive.org/web/20090304151802/http://www.pbs.org/wgbh/amex/influenza/sfeature/latest.html |date=2009-03-04 }}
* [http://www.medsci.org/v02p0087.htm An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic] {{Webarchive|url=https://web.archive.org/web/20230603185956/https://www.medsci.org/v02p0087.htm |date=2023-06-03 }}
* [http://www.gi.alaska.edu/ScienceForum/ASF13/1386.html Alaska Science Forum - Permafrost Preserves Clues to Deadly 1918 Flu] {{Webarchive|url=https://web.archive.org/web/20120419072040/http://www2.gi.alaska.edu/ScienceForum/ASF13/1386.html |date=2012-04-19 }}
* [http://www.vlib.us/medical/mja.htm Pathology of Influenza in France, 1920 Report] {{Webarchive|url=https://web.archive.org/web/20060614000323/http://www.vlib.us/medical/mja.htm |date=2006-06-14 }}
* [http://www.cosmosmagazine.com/node/694 "Deadly secret of 1918 flu virus unmasked"] {{Webarchive|url=https://web.archive.org/web/20071228220419/http://www.cosmosmagazine.com/node/694 |date=2007-12-28 }}, ''Cosmos'' magazine, September 2006
* [http://www.startribune.com/blogs/oldnews/?p=41 Yesterday's News blog] {{Webarchive|url=https://web.archive.org/web/20070314054111/http://www.startribune.com/blogs/oldnews/?p=41 |date=2007-03-14 }}, 1918 newspaper account on impact of flu on Minneapolis
* [http://news.bbc.co.uk/1/hi/health/6271833.stm "Lethal secrets of 1918 flu virus"] {{Webarchive|url=https://web.archive.org/web/20230530060953/http://news.bbc.co.uk/1/hi/health/6271833.stm |date=2023-05-30 }} BBC News, January 2007
* [http://www.news.wisc.edu/13360.html "Study uncovers a lethal secret of 1918 influenza virus"] {{Webarchive|url=https://web.archive.org/web/20070122062720/http://www.news.wisc.edu/13360.html |date=2007-01-22 }} University of Wisconsin - Madison, January 17, 2007
* [http://www.translational-medicine.com/content/2/1/3 "The site of origin of the 1918 influenza pandemic and its public health implications"] {{Webarchive|url=https://web.archive.org/web/20081025094308/http://www.translational-medicine.com/content/2/1/3 |date=2008-10-25 }} Journal of Translational Medicine, January 20, 2004
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[[Kategori:Penyakit]]
[[Kategori:PandemikPandemi]]
[[Kategori:Influenza]]
[[Kategori:1918]]
 
 
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