Penggumpalan darah: Perbedaan antara revisi

Konten dihapus Konten ditambahkan
ESCa (bicara | kontrib)
kTidak ada ringkasan suntingan
ESCa (bicara | kontrib)
k idfy
Baris 2:
 
<!--
Coagulation is highly [[conservation (genetics)|conserved]] throughout biology; in all [[mammal]]s, coagulation involves both a cellular (platelet) and a [[protein]] (coagulation factor) component. The system in humans has been the most extensively researched and is therefore the best understood.
 
Coagulation begins almost instantly after an injury to the blood vessel has damaged the [[endothelium]] (lining of the vessel), this releases [[phospholipid]] components called [[tissue factor]] and [[fibrinogen]] that initiate a chain reaction. [[Platelet]]s immediately form a plug at the site of injury; this is called ''primary hemostasis''. ''Secondary hemostasis'' occurs simultaneously: Proteins in the [[blood plasma]], called ''coagulation factors'' or ''clotting factors'', respond in a complex cascade to form [[fibrin]] strands, which strengthen the platelet plug.<ref name=Furie>{{cite journal |author=Furie B, Furie BC |title=Thrombus formation in vivo |journal=J. Clin. Invest. |volume=115 |issue=12 |pages=3355–62 |year=2005 |pmid=16322780|doi=10.1172/JCI26987|url=http://www.jci.org/cgi/content/full/115/12/3355}} {{PMC|1297262}}</ref>
-->
 
Proses koagulasi terjadi segera setelah terjadinya [[luka]] pada [[pembuluh darah]] dengan rusaknya [[endotelium]] ([[bahasa Inggris|en]]:''endothelium''). Langkah awal koagulasi adalah dengan pelepasan komponen [[fosfolipid]] ([[bahasa Inggris|en]]:''phospholipid'') yang disebut [[faktor jaringan]] ([[bahasa Inggris|en]]:''tissue factor'') dan [[fibrinogen]] sebagai inisiasi sebuah [[reaksi berantai]]]. Segera setelah itu [[keping darah]] bereaksi membentuk penyumbat pada permukaan luka, reaksi ini disebut [[hemostasis]] awal ([[bahasa Inggris|en]]:''primary''). Hemostasis lanjutan ([[bahasa Inggris|en]]:''secondary'') terjadi hampir bersamaan:[[protein]] dalam [[plasma darah]] yang disebut [[faktor koagulasi]] ([[bahasa Inggris|en]]:''clotting factor'') merespon secara berjenjang dan sangat rumit untuk membentuk jaring-jaring [[fibrin]] yang memperkuat penyumbatan keping darah.<ref name=Furie>{{cite journal |author=Furie B, Furie BC |title=Thrombus formation in vivo |journal=J. Clin. Invest. |volume=115 |issue=12 |pages=3355–62 |year=2005 |pmid=16322780|doi=10.1172/JCI26987|url=http://www.jci.org/cgi/content/full/115/12/3355}} {{PMC|1297262}}</ref>
 
==Referensi==