CGA adalah nama berkas gen pada kromosom 6 lokasi 6q12-q21.[3]
CGA |
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Pengidentifikasi |
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Alias | CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA, Chorionic gonadotropin alpha, glycoprotein hormones, alpha polypeptide, Alpha subunit of glycoprotein hormones, GPA1 |
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ID eksternal | OMIM: 118850 MGI: 88390 HomoloGene: 587 GeneCards: CGA |
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Ontologi gen |
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Fungsi molekuler | • GO:0001948, GO:0016582 Ikatan protein plasma • hormone activity • follicle-stimulating hormone activity
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Komponen seluler | • Golgi lumen • extracellular region • extracellular space • follicle-stimulating hormone complex
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Proses biologis | • cell-cell signaling • peptide hormone processing • positive regulation of cell population proliferation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0072468 signal transduction • positive regulation of cell migration • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • positive regulation of steroid biosynthetic process • thyroid hormone generation
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Sumber:Amigo / QuickGO |
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Ortolog |
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Spesies | Manusia | Tikus |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lokasi (UCSC) | n/a | n/a |
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Pencarian PubMed | [1] | [2] |
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Wikidata |
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Empat hormon glikoprotein yakni gonadotropin, lutropin, FSH, TSH merupakan protein dimer yang terdiri dari sub-unit alfa dan beta. CGA merupakan berkas gen yang mengekspresikan protein sub-unit alfa yang identik untuk keempat hormon tersebut, sedangkan sub-unit beta diekspresikan oleh berkas gen yang berlainan.