EIF2AK4

EIF2AK4
Struktur yang tersedia
PDB	Pencarian Ortolog: PDBe RCSB
Daftar kode id PDB
	1UKX, 4OTN
Pengidentifikasi
Alias	EIF2AK4, GCN2, PVOD2, eukaryotic translation initiation factor 2 alpha kinase 4
ID eksternal	OMIM: 609280 MGI: 1353427 HomoloGene: 40891 GeneCards: EIF2AK4
Lokasi gen (Tikus)
Kr.	Kromosom 2 (tikus)
Akhir	118,305,715 bp
Ontologi gen
Fungsi molekuler	• transferase activity; • nucleotide binding; • protein kinase activity; • tRNA binding; • kinase activity; • protein serine/threonine kinase activity; • RNA binding; • ATP binding; • eukaryotic translation initiation factor 2alpha kinase activity;
Komponen seluler	• sitoplasma; • polysome; • cytosolic ribosome;
Proses biologis	• positive regulation of translational initiation in response to starvation; • adaptive immune response; • negative regulation of neuron differentiation; • positive regulation of long-term synaptic potentiation; • positive regulation of adaptive immune response; • negative regulation of translational initiation in response to stress; • negative regulation of translational initiation; • Fosforilasi; • immune system process; • cellular response to UV; • cellular response to amino acid starvation; • negative regulation of CREB transcription factor activity; • regulation of feeding behavior; • belajar; • perkembangan sistem saraf; • viral translation; • neuron projection extension; • protein phosphorylation; • cellular response to cold; • long-term memory; • defense response to virus; • cellular response to leucine starvation; • eiF2alpha phosphorylation in response to endoplasmic reticulum stress; • induction by virus of host autophagy; • protein autophosphorylation; • Siklus sel; • negative regulation by host of viral genome replication; • GO:0022415 viral process; • regulation of translation; • regulation of translational initiation; • positive regulation of defense response to virus by host; • T cell activation involved in immune response; • DNA damage checkpoint signaling; • regulation of translational initiation by eIF2 alpha phosphorylation;
	Sumber:Amigo / QuickGO
Ortolog
	440275
	27103
	ENSG00000128829
	ENSMUSG00000005102
	Q9P2K8
	Q9QZ05
	NM_001013703
	NM_001177806; NM_013719; NM_001355383
	NP_001013725
	NP_001171277; NP_038747; NP_001342312
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus