KCNK3

Potassium channel subfamily K member 3 adalah protein yang disandikan oleh gen KCNK3 dalam tubuh manusia.^[1]^[2]^[3]^[4] KCNK3 diketahui telah berinteraksi dengan YWHAB^[5] dan S100A10.^[6]

Beberapa mutasi terhadap gen ini telah ditemukan oleh para peneliti. Salah satunya adalah mutasi yang dapat menyebabkan hipertensi paru.^[7]

Referensi

^ Duprat F, Lesage F, Fink M, Reyes R, Heurteaux C, Lazdunski M (Dec 1997). "TASK, a human background K+ channel to sense external pH variations near physiological pH". EMBO J. 16 (17): 5464–71. doi:10.1093/emboj/16.17.5464. PMC 1170177  . PMID 9312005.
^ Lesage F, Lazdunski M (Oct 1998). "Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23". Genomics. 51 (3): 478–9. doi:10.1006/geno.1998.5397. PMID 9721223.
^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.
^ "Entrez Gene: KCNK3 potassium channel, subfamily K, member 3".
^ O'Kelly, Ita; Butler Margaret H; Zilberberg Noam; Goldstein Steve A N (Nov 2002). "Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals". Cell. United States. 111 (4): 577–88. doi:10.1016/S0092-8674(02)01040-1. ISSN 0092-8674. PMID 12437930.
^ Girard, Christophe; Tinel Norbert; Terrenoire Cécile; Romey Georges; Lazdunski Michel; Borsotto Marc (Sep 2002). "p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1". EMBO J. England. 21 (17): 4439–48. doi:10.1093/emboj/cdf469. ISSN 0261-4189. PMC 125412  . PMID 12198146.
^ Ma L, Roman-Campos D, Austin ED. (2013). "A novel channelopathy in pulmonary arterial hypertension". N Engl J Med. (dalam bahasa Inggris) (369): 351-361.

[pmid9312005-1] Duprat F, Lesage F, Fink M, Reyes R, Heurteaux C, Lazdunski M (Dec 1997). "TASK, a human background K+ channel to sense external pH variations near physiological pH". EMBO J. 16 (17): 5464–71. doi:10.1093/emboj/16.17.5464. PMC 1170177  . PMID 9312005.

[pmid9721223-2] Lesage F, Lazdunski M (Oct 1998). "Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23". Genomics. 51 (3): 478–9. doi:10.1006/geno.1998.5397. PMID 9721223.

[pmid16382106-3] Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.

[entrez-4] "Entrez Gene: KCNK3 potassium channel, subfamily K, member 3".

[pmid12437930-5] O'Kelly, Ita; Butler Margaret H; Zilberberg Noam; Goldstein Steve A N (Nov 2002). "Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals". Cell. United States. 111 (4): 577–88. doi:10.1016/S0092-8674(02)01040-1. ISSN 0092-8674. PMID 12437930.

[pmid12198146-6] Girard, Christophe; Tinel Norbert; Terrenoire Cécile; Romey Georges; Lazdunski Michel; Borsotto Marc (Sep 2002). "p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1". EMBO J. England. 21 (17): 4439–48. doi:10.1093/emboj/cdf469. ISSN 0261-4189. PMC 125412  . PMID 12198146.

[Ma_2013-7] Ma L, Roman-Campos D, Austin ED. (2013). "A novel channelopathy in pulmonary arterial hypertension". N Engl J Med. (dalam bahasa Inggris) (369): 351-361.

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