Koronavirus berkaitan sindrom pernapasan akut berat
Koronavirus berkaitan sindrom pernapasan akut berat (SARSr-CoV atau SARS-CoV)[note 1] adalah spesies koronavirus yang menjangkiti manusia, kelelawar, dan beberapa mamalia tertentu.[2][3] Virus ini adalah virus RNA beruntai tunggal sense positif berselubung yang memasuki sel inangnya dengan mengikat reseptor enzim pengubah angiotensin 2 (ACE2).[4] Virus ini adalah anggota genus Betacoronavirus dan subgenus Sarbecovirus.[5][6]
Koronavirus berkaitan sindrom pernapasan akut berat | |
---|---|
Mikrograf elektron transmisi dari koronavirus berkaitan SARS yang muncul dari sel inang yang dikultur di laboratorium | |
Klasifikasi virus | |
Takson tak dikenal (perbaiki): | Sarbecovirus |
Spesies: | Koronavirus berkaitan sindrom pernapasan akut berat
|
Galur | |
| |
Sinonim | |
|
Dua galur virus ini telah menyebabkan wabah penyakit pernapasan parah pada manusia, yaitu koronavirus sindrom pernapasan akut berat (SARS-CoV atau SARS-CoV-1), yang menyebabkan wabah sindrom pernapasan akut berat (SARS) pada 2002–2004, dan koronavirus sindrom pernapasan akut berat 2 (SARS-CoV-2), yang menyebabkan pandemi terkini penyakit koronavirus 2019 (COVID-19).[7][8] Terdapat ratusan galur SARS-CoV lainnya, yang semuanya hanya diketahui menjangkiti spesies bukan manusia, yaitu bats are a major reservoir of many strains of SARS-related coronaviruses, and several strains have been identified in palm civets, which were likely ancestors of SARS-CoV.[7][9]
Lihat pula
sunting- Koronavirus mirip SARS WIV1 (SL-CoV-WIV1)
Catatan
sunting- ^ The terms SARSr-CoV and SARS-CoV are sometimes used interchangeably, especially prior to the discovery of SARS-CoV-2.
Referensi
sunting- ^ "ICTV Taxonomy history: Severe acute respiratory syndrome-related coronavirus". International Committee on Taxonomy of Viruses (ICTV) (dalam bahasa Inggris). Diakses tanggal 27 January 2019.
- ^ Branswell H (9 November 2015). "SARS-like virus in bats shows potential to infect humans, study finds". Stat News. Diakses tanggal 20 February 2020.
- ^ Wong AC, Li X, Lau SK, Woo PC (February 2019). "Global Epidemiology of Bat Coronaviruses". Viruses. 11 (2): 174. doi:10.3390/v11020174. PMC 6409556 . PMID 30791586.
Most notably, horseshoe bats were found to be the reservoir of SARS-like CoVs, while palm civet cats are considered to be the intermediate host for SARS-CoVs [43,44,45].
- ^ Kesalahan pengutipan: Tag
<ref>
tidak sah; tidak ditemukan teks untuk ref bernamapmid24172901
- ^ "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV) (dalam bahasa Inggris). October 2018. Diakses tanggal 13 January 2019.
- ^ Woo PC, Huang Y, Lau SK, Yuen KY (August 2010). "Coronavirus genomics and bioinformatics analysis". Viruses. 2 (8): 1804–20. doi:10.3390/v2081803. PMC 3185738 . PMID 21994708.
Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein.
- ^ a b Coronaviridae Study Group of the International Committee on Taxonomy of Viruses (March 2020). "The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2". Nature Microbiology. 5 (4): 536–544. doi:10.1038/s41564-020-0695-z . PMC 7095448 . PMID 32123347.
- ^ Kohen, Jon; Kupferschmidth, Kai (28 February 2020). "Strategies shift as coronavirus pandemic looms". Science. 367 (6481): 962–963. Bibcode:2020Sci...367..962C. doi:10.1126/science.367.6481.962 . PMID 32108093.
- ^ Lau SK, Li KS, Huang Y, Shek CT, Tse H, Wang M, et al. (March 2010). "Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events". Journal of Virology. 84 (6): 2808–19. doi:10.1128/JVI.02219-09 . PMC 2826035 . PMID 20071579.
Bacaan lainnya
sunting- Peiris JS, Lai ST, Poon LL, Guan Y, Yam LY, Lim W, et al. (April 2003). "Coronavirus as a possible cause of severe acute respiratory syndrome". Lancet. 361 (9366): 1319–25. doi:10.1016/s0140-6736(03)13077-2 . PMC 7112372 . PMID 12711465.
- Rota PA, Oberste MS, Monroe SS, Nix WA, Campagnoli R, Icenogle JP, et al. (May 2003). "Characterization of a novel coronavirus associated with severe acute respiratory syndrome". Science. 300 (5624): 1394–9. Bibcode:2003Sci...300.1394R. doi:10.1126/science.1085952 . PMID 12730500.
- Marra MA, Jones SJ, Astell CR, Holt RA, Brooks-Wilson A, Butterfield YS, et al. (May 2003). "The Genome sequence of the SARS-associated coronavirus". Science. 300 (5624): 1399–404. Bibcode:2003Sci...300.1399M. doi:10.1126/science.1085953 . PMID 12730501.
- Snijder EJ, Bredenbeek PJ, Dobbe JC, Thiel V, Ziebuhr J, Poon LL, et al. (August 2003). "Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage". Journal of Molecular Biology. 331 (5): 991–1004. CiteSeerX 10.1.1.319.7007 . doi:10.1016/S0022-2836(03)00865-9. PMID 12927536.
- Yount B, Roberts RS, Lindesmith L, Baric RS (August 2006). "Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: engineering a recombination-resistant genome". Proceedings of the National Academy of Sciences of the United States of America. 103 (33): 12546–51. Bibcode:2006PNAS..10312546Y. doi:10.1073/pnas.0605438103. PMC 1531645 . PMID 16891412.
- Thiel V, ed. (2007). Coronaviruses: Molecular and Cellular Biology (edisi ke-1st). Caister Academic Press. ISBN 978-1-904455-16-5.
- Enjuanes L, Sola I, Zúñiga S, Almazán F (2008). "Coronavirus Replication and Interaction with Host". Dalam Mettenleiter TC, Sobrino F. Animal Viruses: Molecular Biology. Caister Academic Press. ISBN 978-1-904455-22-6.
Pranala luar
sunting- WHO press release identifying and naming the SARS virus
- The SARS virus genetic map Diarsipkan 2006-08-18 di Wayback Machine.
- Science special on the SARS virus (free content: no registration required)
- McGill University SARS Resources di Wayback Machine (diarsipkan tanggal 1 March 2005)
- U.S. Centers for Disease Control and Prevention (CDC) SARS home
- World Health Organization on alert