Karsinoma sel skuamosa: Perbedaan antara revisi

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'''Karsinoma sel skuamosa''' ([[bahasa Inggris]]: ''Squamous cell carcinoma'', '''SCC''' atau '''SqCC''') merupakan salah satu jenis [[kanker kulit]] selain [[kanker sel basal]] dan [[melanoma]].<ref name=NCI2013TxPro>{{cite web|title=Skin Cancer Treatment (PDQ®)|url=http://www.cancer.gov/cancertopics/pdq/treatment/skin/HealthProfessional/page1/AllPages|website=NCI|accessdate=30 June 2014|date=2013-10-25|deadurl=no|archiveurl=https://web.archive.org/web/20140705234200/http://www.cancer.gov/cancertopics/pdq/treatment/skin/HealthProfessional/page1/AllPages|archivedate=5 July 2014|df=}}</ref> Kanker ini biasanya tampak seperti bengkak besar, tetapi juga dapat membentuk [[borok]].<ref name=Lyn2011>{{cite book|author1=Lynne M Dunphy|title=Primary Care: The Art and Science of Advanced Practice Nursing|date=2011|publisher=F.A. Davis|isbn=9780803626478|page=242|url=https://books.google.com/books?id=RR1hAQAAQBAJ&pg=PA242|deadurl=no|archiveurl=https://web.archive.org/web/20160520044442/https://books.google.com/books?id=RR1hAQAAQBAJ&pg=PA242|archivedate=2016-05-20|df=}}</ref> Serangan kanker ini biasanya berlangsung selama berbulan-bulan.<ref name=Fer2017/> Kanker kulit sel skuamosa lebih dapat [[metastasis|menyebar ke wilayah sekitar]] daripada kanker sel basal.<ref name=Cak2012>{{cite journal|last1=Cakir|first1=BÖ|last2=Adamson|first2=P|last3=Cingi|first3=C|title=Epidemiology and economic burden of nonmelanoma skin cancer.|journal=Facial plastic surgery clinics of North America|date=November 2012|volume=20|issue=4|pages=419–22|pmid=23084294|doi=10.1016/j.fsc.2012.07.004}}</ref>
 
Faktor risiko terbesar adalah paparan terhadap [[radiasi ultraviolet]] dari Matahari.<ref name=Ga2015/> Faktor risiko lain adalah [[parut|bekas luka]] dari sebelumnya, luka [[kronis]], [[keratosis asitinik]], kulit yang lebih terang, [[penyakit Bowen]], terpapar [[arsen]], fungsi sistem kekebalan yang buruk, karsinoma sel basal dari sebelumnya, dan [[infeksi HPV]].<ref name=Ga2015/><ref>{{Cite book|url=https://www.jstor.org/stable/j.ctt1g69xq0.9|title=Textbook of Plastic and Reconstructive Surgery|last=Opel|first=Sophia|date=2016|publisher=UCL Press|isbn=9781910634394|edition=1|pages=65}}</ref> Risiko dari radiasi ultraviolet biasanya diakibatkan oleh paparan secara penuh.<ref name=UV2010>{{cite journal|last1=Gallagher|first1=RP|last2=Lee|first2=TK|last3=Bajdik|first3=CD|last4=Borugian|first4=M|title=Ultraviolet radiation.|journal=Chronic diseases in Canada|date=2010|volume=29 Suppl 1|pages=51–68|pmid=21199599}}</ref> Alat untuk berjemur di dalam ruang juga menjadi sumber radiasi ultraviolet di negara-negara Barat.<ref name="UV2010"/> Kanker ini berasal dari [[sel skuamosa]] di dalam kulit manusia.<ref name=NCI2016Def>{{cite web|title=NCI Dictionary of Cancer Terms|url=https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=46595|website=National Cancer Institute|accessdate=9 November 2016|deadurl=no|archiveurl=https://web.archive.org/web/20161109230919/https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=46595|archivedate=9 November 2016|df=}}</ref> Diagnosis biasanya didasarkan pada pemeriksaan kulit dan dikonfirmasi oleh [[biopsi jaringan]].<ref name=Ga2015/><ref name=NCI2017Diag>{{cite web|title=Skin Cancer Treatment|url=https://www.cancer.gov/types/skin/patient/skin-treatment-pdq|website=National Cancer Institute|accessdate=2 July 2017|language=en|date=21 June 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170704222639/https://www.cancer.gov/types/skin/patient/skin-treatment-pdq|archivedate=4 July 2017|df=}}</ref>
 
Metode efektif untuk mencegah kanker sel skuamosa adalah mengurangi radiasi ultraviolet dan penggunaan [[tabir surya]].<ref name=WCR2014/><ref name=Jou2012>{{cite journal|last1=Jou|first1=PC|last2=Feldman|first2=RJ|last3=Tomecki|first3=KJ|title=UV protection and sunscreens: what to tell patients.|journal=Cleveland Clinic journal of medicine|date=June 2012|volume=79|issue=6|pages=427–36|pmid=22660875|doi=10.3949/ccjm.79a.11110}}</ref> Kanker ini biasanya dikeluarkan dengan melakukan operasi.<ref name=Ga2015/> Operasi dapat dilakukan lewat pemotongan sederhana jika sel kankernya kecil, tetapi jika tidak [[operasi Mohs]] perlu dilakukan.<ref name=Ga2015/> Pilihan lain adalah [[kriosurgeri]] dan [[terapi radiasi]].<ref name=NCI2017Tx>{{cite web|title=Skin Cancer Treatment|url=https://www.cancer.gov/types/skin/patient/skin-treatment-pdq#link/_119_toc|website=National Cancer Institute|accessdate=2 July 2017|language=en|date=21 June 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170704222639/https://www.cancer.gov/types/skin/patient/skin-treatment-pdq#link/_119_toc|archivedate=4 July 2017|df=}}</ref> Jika penyakit telah menyebar, [[kemotrapi]] juga dapat dilakukan.<ref name=NCI2017Tx/>
 
Metode efektif untuk mencegah kanker sel skuamosa adalah mengurangi radiasi ultraviolet dan penggunaan [[tabir surya]].<ref name=WCR2014>{{cite book|title=World Cancer Report 2014.|url=https://archive.org/details/worldcancerrepor0000unse_p0u5|date=2014|publisher=World Health Organization|isbn=9283204298|pages=Chapter 5.14}}</ref><ref name=Jou2012>{{cite journal|last1=Jou|first1=PC|last2=Feldman|first2=RJ|last3=Tomecki|first3=KJ|title=UV protection and sunscreens: what to tell patients.|journal=Cleveland Clinic journal of medicine|date=June 2012|volume=79|issue=6|pages=427–36|pmid=22660875|doi=10.3949/ccjm.79a.11110}}</ref> Kanker ini biasanya dikeluarkan dengan melakukan operasi.<ref name=Ga2015/> Operasi dapat dilakukan lewat pemotongan sederhana jika sel kankernya kecil, tetapi jika tidak [[operasi Mohs]] perlu dilakukan.<ref name=Ga2015/> Pilihan lain adalah [[kriosurgeri]] dan [[terapi radiasi]].<ref name=NCI2017Tx>{{cite web|title=Skin Cancer Treatment|url=https://www.cancer.gov/types/skin/patient/skin-treatment-pdq#link/_119_toc|website=National Cancer Institute|accessdate=2 July 2017|language=en|date=21 June 2017|deadurl=no|archiveurl=https://web.archive.org/web/20170704222639/https://www.cancer.gov/types/skin/patient/skin-treatment-pdq#link/_119_toc|archivedate=4 July 2017|df=}}</ref> Jika penyakit telah menyebar, [[kemotrapikemoterapi]] juga dapat dilakukan.<ref name=NCI2017Tx/>
 
Pada tahun 2015, terdapat sekitar 2,2 juta pengidap kanker sel skuamosa<ref name=GBD2015Pre/> atau sekitar 20% kasus kanker.<ref>{{cite journal|last1=Stratigos|first1=A|last2=Garbe|first2=C|last3=Lebbe|first3=C|last4=Malvehy|first4=J|last5=del Marmol|first5=V|last6=Pehamberger|first6=H|last7=Peris|first7=K|last8=Becker|first8=JC|last9=Zalaudek|first9=I|last10=Saiag|first10=P|last11=Middleton|first11=MR|last12=Bastholt|first12=L|last13=Testori|first13=A|last14=Grob|first14=JJ|last15=European Dermatology Forum|first15=(EDF).|last16=European Association of Dermato-Oncology|first16=(EADO).|last17=European Organization for Research and Treatment of Cancer|first17=(EORTC).|title=Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline.|journal=European Journal of Cancer|date=September 2015|volume=51|issue=14|pages=1989–2007|pmid=26219687}}</ref> Sekitar 12% laki-laki dan 7% wanita di Amerika Serikat pernah mengidap kanker ini.<ref name=Ga2015>{{cite journal|last1=Gandhi|first1=SA|last2=Kampp|first2=J|title=Skin Cancer Epidemiology, Detection, and Management.|journal=The Medical clinics of North America|date=November 2015|volume=99|issue=6|pages=1323–35|pmid=26476255}}</ref> Prognosisnya biasanya baik, tetapi jika menyebar, tingkat kelangsungan hidup selama lima tahun berkisar pada angka 34%.<ref name=Fer2017/><ref name=WCR2014/> Pada tahun 2015, penyakit ini mengakibatkan 51.900 kematian di seluruh dunia.<ref name=GBD2015De/> Mereka yang didiagnosis biasanya berumur 66 tahun.<ref name=Fer2017>{{cite book|last1=Ferri|first1=Fred F.|title=Ferri's Clinical Advisor 2017 E-Book: 5 Books in 1|date=2016|publisher=Elsevier Health Sciences|isbn=9780323448383|page=1199|url=https://books.google.ca/books?id=rRhCDAAAQBAJ&pg=PA1199|accessdate=2 July 2017|language=en|deadurl=no|archiveurl=https://web.archive.org/web/20170829075945/https://books.google.ca/books?id=rRhCDAAAQBAJ&pg=PA1199|archivedate=29 August 2017|df=}}</ref> Setelah berhasil ditangani, terdapat kemungkinan besar bahwa kanker ini akan kembali muncul pada pengidapnya.<ref name=Ga2015/>
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* [http://www.skincancer.org/squamous-cell-carcinoma.html Information on Squamous Cell Carcinoma from The Skin Cancer Foundation]
* [http://www.dermnetnz.org/lesions/squamous-cell-carcinoma.html DermNet NZ: Squamous cell carcinoma]
* [http://www.skintherapyletter.com/2004/9.4/2.html Squamous cell carcinoma in transplant recipients] {{Webarchive|url=https://web.archive.org/web/20101129011402/http://www.skintherapyletter.com/2004/9.4/2.html |date=2010-11-29 }}
* [http://www.kidneycancerresource.com/ Including TCC, CIS and papillary tumour SCC]
* [http://www.cancernetwork.com/cancer-management-11/chapter04/article/10165/1402663 Cancer Management Handbook: Head and Neck Tumors] {{Webarchive|url=https://web.archive.org/web/20090720201346/http://www.cancernetwork.com/cancer-management-11/chapter04/article/10165/1402663 |date=2009-07-20 }}
* [http://www.sinustumor.org/tumors/snuc/ SinusTumor.org] - an educational site that provides information about sinus tumor
{{Female genital neoplasia}}
 
[[Kategori:Patologi anatomi]]
[[Kategori:KanserKanker]]