[[Berkas:Poster_of_Edward_Said.jpg|al=Tattered poster on wall, partially covered by graffiti.|ka|jmpl|300x300px|''In Memoriam Edward Wadie Saïd'': poster [[Inisiatif Nasional Palestina]] di [[Tembok Pemisah Israel|tembok Tepi Barat Israel]]]]Pada tanggal 24 September 2003, Said meninggal,padadi usia 67 tahun di New York City setelah menderita penyakit [[leukemia limfositik kronis]] selama 12 tahun.<ref name="nyt2">{{Cite news|last=Bernstein|first=Richard|date=26 September 2003|title=Edward W. Said, Literary Critic and Advocate for Palestinian Independence, Dies at 67|url=https://www.nytimes.com/2003/09/26/arts/edward-w-said-literary-critic-advocate-for-palestinian-independence-dies-67.html|work=The New York Times|page=23|archive-url=https://web.archive.org/web/20120520040836/https://www.nytimes.com/2003/09/26/arts/edward-w-said-literary-critic-advocate-for-palestinian-independence-dies-67.html?pagewanted=all&src=pm|archive-date=20 May 2012|access-date=6 June 2013|url-status=live}}</ref> Ia meninggalkan istrinya, Mariam C. Said, putranya, Wadie Said, dan putrinya, Najla Said.<ref name="ruthven">{{Cite news|last=Ruthven|first=Malise|date=26 September 2003|title=Obituary: Edward Said|url=https://www.theguardian.com/news/2003/sep/26/guardianobituaries.highereducation|work=[[The Guardian]]|archive-url=https://web.archive.org/web/20230114153120/https://www.theguardian.com/news/2003/sep/26/guardianobituaries.highereducation|archive-date=14 January 2023|access-date=6 June 2013|url-status=live}}</ref><ref>{{Cite web|last=<!--No author name given.-->|date=26 September 2003|title=Columbia Community Mourns Passing of Edward Said, Beloved and Esteemed University Professor|url=http://www.columbia.edu/cu/news/03/09/edwardSaid_2.html|website=Columbia News|publisher=Columbia University|archive-url=https://web.archive.org/web/20031002225327/http://www.columbia.edu/cu/news/03/09/edwardSaid_2.html|archive-date=2 October 2003|access-date=6 June 2013|url-status=dead}}</ref><ref>{{Cite news|last=Feeney|first=Mark|date=26 September 2003|title=Edward Said, critic, scholar, Palestinian advocate; at 67|url=http://archive.boston.com/news/education/higher/articles/2003/09/26/edward_said_critic_scholar_palestinian_advocate_at_67/|work=[[The Boston Globe]]|archive-url=https://web.archive.org/web/20220407000732/http://archive.boston.com/news/education/higher/articles/2003/09/26/edward_said_critic_scholar_palestinian_advocate_at_67/|archive-date=7 April 2022|access-date=6 June 2013|url-status=live}}</ref> Para tokoh yang memberikan euologi antara lain [[Alexander Cockburn]] ("Hati yang Kuat dan Penuh Semangat");<ref>{{Cite news|last=Cockburn|first=Alexander|date=25 September 2003|title=Edward Said: A Mighty and Passionate Heart|url=https://www.counterpunch.org/2003/09/25/edward-said-a-mighty-and-passionate-heart/|work=CounterPunch|archive-url=https://web.archive.org/web/20220627174807/https://www.counterpunch.org/2003/09/25/edward-said-a-mighty-and-passionate-heart/|archive-date=27 June 2022|url-status=live}}</ref> [[Seamus Deane]] ("Gaya Humanisme yang Terlambat");<ref>{{Cite journal|last=Deane|first=Seamus|year=2005|title=Edward Said (1935–2003): A Late Style of Humanism|url=https://fieldday.ie/wp-content/uploads/2014/12/SDeaneFDR.pdf|journal=Field Day Review|volume=1|pages=189–202|issn=1649-6507|jstor=30078611|archive-url=https://web.archive.org/web/20220617043929/https://fieldday.ie/wp-content/uploads/2014/12/SDeaneFDR.pdf|archive-date=17 June 2022|url-status=live}}</ref> [[Christopher Hitchens]] ("Salam untuk Edward Said");<ref>{{Cite news|last=Hitchens|first=Christopher|date=26 September 2003|title=A valediction for Edward Said|url=https://slate.com/news-and-politics/2003/09/a-valediction-for-edward-said.html|work=Slate|archive-url=https://web.archive.org/web/20230307033719/https://slate.com/news-and-politics/2003/09/a-valediction-for-edward-said.html|archive-date=7 March 2023|url-status=live}}</ref> [[Tony Hakim|Tony Judt]] ("Kosmopolitan Tanpa Akar");<ref>{{Cite magazine|last=Judt|url-status=live|magazine=The Nation|archive-url=https://web.archive.org/web/20220125135723/https://www.thenation.com/article/archive/rootless-cosmopolitan/|archivedate=25 January 2022}}</ref> [[Michael Wood (akademis)|Michael Wood]] ("Tentang Edward Said");<ref>{{Cite magazine|last=Wood|url-status=live|magazine=London Review of Books|volume=25|archive-url=https://web.archive.org/web/20220630071727/https://www.lrb.co.uk/the-paper/v25/n20/michael-wood/on-edward-said|archivedate=30 June 2022}}</ref> dan [[Tariq Ali]] ("Mengingat Edward Said, 1935–2003").<ref>{{Cite journal|last=Ali|first=Tariq|year=2003|title=Remembering Edward Said, 1935–2003|url=https://newleftreview.org/issues/ii24/articles/tariq-ali-remembering-edward-said|journal=New Left Review|volume=24|pages=59–65|issn=0028-6060|archive-url=https://web.archive.org/web/20221203213707/https://newleftreview.org/issues/ii24/articles/tariq-ali-remembering-edward-said|archive-date=3 December 2022|url-status=live}}</ref> Said dimakamkan di Pemakaman Protestan di Broumana, Jabal Lubnan, Lebanon. Nisannya menunjukkan dia meninggal pada 25 September 2003.
Pada bulan November 2004, [[Universitas Birzeit]] di Palestina mengganti nama sekolah musik mereka menjadi [[Konservatorium Musik Nasional Edward Said]].<ref>Birzeit University, [http://ncm.birzeit.edu/ ''Edward Said National Conservatory of Music''].</ref>