Putresina

Putresina
Nama
	Nama IUPAC (preferensi) Butane-1,4-diamine
	Nama lain 1,4-Diaminobutane
Penanda
Nomor CAS	110-60-1 ;
Model 3D (JSmol)	Gambar interaktif;
3DMet	{{{3DMet}}}
Referensi Beilstein	605282
ChEBI	CHEBI:17148 ;
ChEMBL	ChEMBL46257 ;
ChemSpider	13837702 ;
DrugBank	DB01917 ;
Nomor EC
Referensi Gmelin	1715
IUPHAR/BPS	2388;
KEGG	C02896 ;
MeSH	Putrescine
PubChem CID	1045;
Nomor RTECS	{{{value}}}
Nomor UN	2928
CompTox Dashboard (EPA)	DTXSID4041107 ;
	InChI InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2 Key: KIDHWZJUCRJVML-UHFFFAOYSA-N ;
	SMILES NCCCCN;
Sifat
Rumus kimia	C4H12N2
Massa molar	88,15 g·mol−1
Penampilan	Colourless crystals
Bau	strong, piperidine-like
Densitas	0.877 g/mL
Titik lebur	275 °C (527 °F; 548 K)
Titik didih	4.044 °C; 7.311 °F; 4.317 K
Kelarutan dalam air	Miscible
log P	−0.466
Indeks bias (nD)	1.457
Bahaya
Piktogram GHS
Keterangan bahaya GHS	{{{value}}}
Pernyataan bahaya GHS	H228, H302, H312, H314, H331
Langkah perlindungan GHS	P210, P261, P280, P305+351+338, P310
Titik nyala	51 °C (124 °F; 324 K)
Ambang ledakan	0.98–9.08%
	Dosis atau konsentrasi letal (LD, LC):
LD50 (dosis median)	463 mg kg−1 (oral, rat); 1.576 g kg−1 (dermal, rabbit);
Senyawa terkait
Related alkanamines	Propylamine; Isopropylamine; 1,2-Diaminopropane; 1,3-Diaminopropane; Isobutylamine; tert-Butylamine; n-Butylamine; sec-Butylamine; Pentylamine; Cadaverine;
Senyawa terkait	2-Methyl-2-nitrosopropane
	Kecuali dinyatakan lain, data di atas berlaku pada suhu dan tekanan standar (25 °C [77 °F], 100 kPa).
	verifikasi (apa ini ?)
	Referensi

Putresina, atau tetramethylenediamine, adalah suatu senyawa kimia organik N H₂(CH₂)₄NH₂ (1,4-diaminobutane or butanediamine) yang berbau busuk^[1] yang berhuungan dengan kadaverina; keduanya dihasilkan melalui pemecahan asam amino dalam organisme hidup dan mati dan keduanya merupakan racun dalam dosis besar.^[2]^[3] The two compounds are largely responsible for the foul odor of putrefying flesh, but also contribute to the odor of such processes as bad breath and bacterial vaginosis.^[4] They are also found in semen and some microalgae, together with related molecules like spermine and spermidine.

Referensi

^ Haglund, William (1996). Forensic taphonomy: The Postmortem Fate of Human Remains. CRC Press. hlm. 100. ISBN 0-8493-9434-1.
^ Lewis, Robert Alan (1998). Lewis' Dictionary of Toxicology. CRC Press. hlm. 212. ISBN 1-56670-223-2.
^ Kamhi, Ellen, Ph.D., RN, HNC (2007). Alternative Medicine Magazine's Definitive Guide to Weight Loss. Celestial Arts. hlm. 14. ISBN 1-58761-259-3. Ornithine is converted by bowel bacteria into a toxic substance called putrescine, which in turn degrades into polyamines, such as spermadine, spermine, and cadaverine (literally meaning "the essence of dead cadavers").
^ Yeoman, CJ;Thomas, SM; Miller, ME; Ulanov, AV; Torralba, M; Lucas, S; Gillis, M; Cregger, M; Gomez, A; Ho, M; Leigh, SR; Stumpf, R; Creedon, DJ; Smith, MA; Weisbaum, JS; Nelson, KE; Wilson, BA; White, BA (2013). "A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease". PLOS ONE. 8 (2): e56111. doi:10.1371/journal.pone.0056111. PMC 3566083  . PMID 23405259.

Pranala luar

Putrescine MS Spectrum

Templat:Amino acid metabolism intermediates

[1] Haglund, William (1996). Forensic taphonomy: The Postmortem Fate of Human Remains. CRC Press. hlm. 100. ISBN 0-8493-9434-1.

[2] Lewis, Robert Alan (1998). Lewis' Dictionary of Toxicology. CRC Press. hlm. 212. ISBN 1-56670-223-2.

[3] Kamhi, Ellen, Ph.D., RN, HNC (2007). Alternative Medicine Magazine's Definitive Guide to Weight Loss. Celestial Arts. hlm. 14. ISBN 1-58761-259-3. Ornithine is converted by bowel bacteria into a toxic substance called putrescine, which in turn degrades into polyamines, such as spermadine, spermine, and cadaverine (literally meaning "the essence of dead cadavers").

[4] Yeoman, CJ;Thomas, SM; Miller, ME; Ulanov, AV; Torralba, M; Lucas, S; Gillis, M; Cregger, M; Gomez, A; Ho, M; Leigh, SR; Stumpf, R; Creedon, DJ; Smith, MA; Weisbaum, JS; Nelson, KE; Wilson, BA; White, BA (2013). "A multi-omic systems-based approach reveals metabolic markers of bacterial vaginosis and insight into the disease". PLOS ONE. 8 (2): e56111. doi:10.1371/journal.pone.0056111. PMC 3566083  . PMID 23405259.

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