Klotrimazol
senyawa kimia
Klotrimazol, di antaranya dijual dengan nama merek Canesten, adalah sejenis medikasi antijamur.[1]
Nama sistematis (IUPAC) | |
---|---|
1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-imidazole | |
Data klinis | |
Nama dagang | Desenex, Canesten, others |
AHFS/Drugs.com | monograph |
MedlinePlus | a682753 |
Kat. kehamilan | A(AU) C (by mouth) and B (topical) (US) |
Status hukum | OTC (US) |
Rute | Topical, throat lozenge |
Data farmakokinetik | |
Bioavailabilitas | Poor absorption by mouth (lozenge), negligible absorption through intact skin (topical) |
Ikatan protein | 90% |
Metabolisme | Liver |
Waktu paruh | 2 hours |
Pengenal | |
Nomor CAS | 23593-75-1 |
Kode ATC | A01AB18 D01AC01 G01AF02 QJ02AB90 |
PubChem | CID 2812 |
Ligan IUPHAR | 2330 |
DrugBank | DB00257 |
ChemSpider | 2710 |
UNII | G07GZ97H65 |
KEGG | D00282 |
ChEBI | CHEBI:3764 |
ChEMBL | CHEMBL104 |
Data kimia | |
Rumus | C22H17ClN2 |
Massa mol. | 344.837 g/mol |
| |
Data fisik | |
Titik lebur | 147–149 °C (297–300 °F) |
Referensi
- ^ American Society of Health-System Pharmacists (8 Februari 2016). "Clotrimazole Monograph for Professionals". www.drugs.com. Diarsipkan dari versi asli tanggal 28 October 2016. Diakses tanggal 28 October 2016.