Daftar tingkat kematian kasus penyakit manusia
Ini adalah daftar tingkat fatalitas kasus (CFR) penyakit manusia. CFR adalah angka kematian yang disebabkan oleh penyakit tertentu pada periode waktu tertentu dibagi jumlah kasus dari penyakit tersebut. Data didasarkan pada pasien yang dirawat secara optimal dan mengecualikan kasus terisolasi atau wabah kecil, kecuali dinyatakan sebaliknya.
Daftar ini belum tentu lengkap. Anda dapat membantu Wikipedia dengan mengembangkannya. (July 2012) |
Penyakit | Penyebab | Pengobatan | Tingkat kematian | Catatan | Referensi |
---|---|---|---|---|---|
Transmissible spongiform encephalopathies | Prion | Belum ada pengobatan | 100% | Includes Creutzfeldt–Jakob disease and all its variants, fatal familial insomnia, kuru, Gerstmann–Sträussler–Scheinker syndrome and others. | [1] |
Fibrodysplasia Ossificans Progressiva | Autosom | Belum ada pengobatan | ~ 100% | Death almost always results from complications of FOP, life expectancy is about 40 years | [2] |
Tay–Sachs disease (pre-adult) | Enzim | Belum ada pengobatan | ~ 100% | Even with the most high quality care, infants with Tay–Sachs disease usually die within a few years of displaying the first symptoms. Juvenile with the disease are likely to die from the ages 5–15, while those who develop the disease as adults will probably be largely unaffected. | [3] |
African trypanosomiasis | Parasit (Trypanosoma brucei) | Belum ditemukan pengobatan khusus | ~ 100% | [4] | |
Visceral leishmaniasis | Parasit (Leishmania) | Belum ditemukan pengobatan khusus | ~ 100% | [5] | |
Primary amoebic meningoencephalitis, Naegleria fowleri | Parasit (Naegleria fowleri) | Belum ditemukan pengobatan khusus | ~ 99% | Amphotericin B has shown efficacy in the limited survivorship population. Around 7 documented survivors | |
Rabies | Virus (Lyssavirus) | Belum ditemukan pengobatan khusus | ~ 99% | Preventable with vaccines down to ~0% CFR and treatable with PEP but, once the symptoms manifest, the CFR is near 100%. Around 16 documented survivors after symptom onset, all but 3 did not receive any Rabies (specific) treatment at any time before symptom onset. Of those 3, only 1 survived without the use of a therapeutic coma | [6] |
Balamuthia | Parasit (B. mandrillaris) | Oportunistik & Belum ditemukan pengobatan khusus [7] | ~ 99% | 2 survivors, both have permanent brain damage. | [8] |
Glanders, septicemic | Bakteri (Burkholderia mallei) | Belum ditemukan pengobatan khusus | 95% | The rate drops significantly to >50% with treatment. | [9] |
Smallpox Variola major – specifically the malignant (flat) or hemorrhagic type | Virus (Variola) | Belum ditemukan pengobatan khusus | ~ 95% | The rate drops significantly to 10% with effective treatments.
Eradicated. |
[10] [11] |
Ebola virus disease – specifically EBOV | Virus (Ebola) | Untreated & Unvaccinated | 83–90% |
Prognosis improved by early supportive treatments as seen in the West African epidemic and the Kivu outbreak. | [12][13] |
AIDS/HIV infection | Virus (HIV) | Belum ditemukan pengobatan khusus | 80–90% | Data are counted during the first 5 years of infection in developed countries. HIV is not lethal on its own but patients are usually killed by respiratory diseases, such as flu or pneumonia because of immunodeficiency caused by HIV virus. | [14] |
Anthrax, specifically the pulmonary form | Bakteri (Bacillus anthracis) | Untreated & Unvaccinated | > 85% | Early treatments lower the CFR to 45% as seen in the 2001 AMERITHRAX letter attacks.
Monoclonal antibodies (Obilotoxaximab & Raxibacumab) could lower this further. |
[10] |
Macanine alphaherpesvirus 1 | Virus (Macacine alphaherpesvirus 1) | Belum ditemukan pengobatan khusus | ~ 80% | Early treatment including aciclovir can improve prognosis. | [15] |
Aspergillosis, invasive pulmonary form | Fungi (Aspergillus) | Opportunistic w/COPD, Tuberculosis and Immunocompromised | 50–90% | [16] | |
Smallpox, Variola major – in pregnant women | Virus (Variola) | Belum ada vaksin | > 65% | [10] | |
Cryptococcal meningitis | Fungi (Cryptococcus) | Co-infection with HIV | 40–60% | 6 month mortality is >=60% with fluconazole-based therapy and 40% with amphotercin-based therapy in research studies in low and middle income countries. | [17] |
Influenza A virus subtype H5N1 | Virus (Influenza) | ~ 60% | [18] | ||
Bubonic plague | Bakteri (Y. pestis) | Belum ditemukan pengobatan khusus & Belum ada vaksin | 5–60% | [10] | |
Tularemia, pneumonic | Bakteri (Francisella tularensis) | Belum ditemukan pengobatan khusus | ≤ 60% | [10] | |
Anthrax, gastrointestinal, intestinal type | Bakteri (Bacillus anthracis) | Untreated & Unvaccinated | > 50% | [10] | |
Marburg virus disease – all outbreaks combined | Virus (Marburg) | Belum ditemukan pengobatan khusus | 23–90% | 23% in 1967 when it was first identified and 90% in 2004-2005 when the worst outbreak of the disease occurred. Galidesivir has shown promise in treating Filoviridae | [19][20] |
Plague, pneumonic | Bakteri (Yersinia Pestis) | Untreated & Unvaccinated | 50% | [10] | |
Tetanus, Generalized | Bakteri (Clostridium tetani) | Untreated & Unvaccinated | 50% | CFR drops to 10–20% with effective treatment. | [21] |
Reye's Syndrome | Tidak diketahui | > 40% | [22] | ||
Baylisascariasis | Parasit (Baylisascaris procyonis) | ~40% | With occurrence of Neural Larva Migrans; early, aggressive treatment necessary for survival, but only 2 full recoveries from NLM ever documented | [23] | |
Plague, septicemic | Bakteri (Yersinia Pestis) | Untreated & Unvaccinated | 30–50% | [10] | |
Hantavirus infection | Virus (Orthohantavirus) | 36% | Ribavirin may be a drug for HPS and HFRS but its effectiveness remains unknown, still, spontaneous recovery is possible with supportive treatment. | ||
Middle Eastern Respiratory Syndrome (MERS) | Virus (MERS-CoV) | 35% | Galidesivir has shown promise in treating Coronaviridae | [24] | |
Tularemia, typhoidal | Bakteri (Francisella tularensis) | Belum ditemukan pengobatan khusus | 3–35% | [10] | |
Eastern equine encephalitis virus | Virus (togavirus) | ~ 33% | [25] | ||
Anthrax, gastrointestinal, oropharyngeal type | Bakteri (Bacillus anthracis) | 10–50% | [10] | ||
Tuberculosis, HIV Negative | Bakteri (Mycobacterium tuberculosis) | Vaksin | 43% | Vaccines have been developed but have been frequently dismissed for having received controversial and improper testing on African populations. | [26] |
Smallpox, Variola major | Virus (Variola) | Belum ada vaksin | 30% | [10] | |
Varicella (chickenpox), in newborns | Virus (Human alphaherpesvirus 3) | Belum ditemukan pengobatan khusus | ~ 30% | Where the mothers develop the disease between 5 days prior to, or 2 days after delivery. | [14] |
Cancer (overall) | Bermacam-macam | Ditemukan | 30% | ~97% will die within five years if untreated.[27] | [28] |
Dengue haemorrhagic fever (DHF) | Virus (Dengue) | Belum ditemukan pengobatan khusus | 26% | Dengue haemorrhagic fever is also known as severe dengue.[29] | [30] |
Hantavirus pulmonary syndrome (HPS) | Virus (Orthohantavirus) | Belum ditemukan pengobatan khusus | ~21% | Galidesivir has shown promise in treating Bunyavirales | [31] |
Leptospirosis | Bakteri ( Leptospira) | < 5–30% | [14] | ||
Legionellosis | Bakteri (Legionella) | ~ 15% | [14] | ||
Anorexia Nervosa | Tidak diketahui | Cohort summary | 16% | [32] | |
Meningococcal disease | Bakteri ( Neisseria meningitidis) | Untreated & Unvaccinated | 10–20% | [33] | |
Typhoid fever | Bakteri (Salmonella) | Untreated & Unvaccinated | 10–20% | [14] | |
Severe acute respiratory syndrome (SARS) | Virus (SARS-CoV) | 11% | Galidesivir has shown promise in treating Coronaviridae | [34] | |
Intestinal capillariasis | Paraasit (Capillaria philippinensis) | Belum ditemukan pengobatan khusus | ~ 10% | [35] | |
Visceral leishmaniasis | Parasit (Leishmania) | ~ 10% | [36] | ||
Botulism | Bakteri ( Clostridium botulinum) | Ditemukan | < 10% | Untreated foodborne botulism is thought to be ~50% | [37] |
Diphtheria, respiratory | Bakteri (Corynebacterium diphtheriae) | Untreated & Unvaccinated | ~ 5–10% | [38] | |
Yellow fever | Virus (Flaviviridae) | Unvaccinated | 7.5% | [39] | |
Coronavirus disease 2019 (COVID-19) | Virus (COVID-19) | ~6.04% | Global, up to 10 April 2020.[40][41] | [42] | |
Pertussis (batuk rejan), bayi di negara berkembang | Bakteri ( Bordetella pertussis) | Unvaccinated | ~ 3.7% | [14] | |
Smallpox, Variola major | Virus (Variola) | Vaksin ditemukan | 3% | [10] | |
1918 (Spanish) flu | Virus (Influenza) | Ditemukan | > 2.5% | [43] | |
Angiostrongyliasis | Parasit (Angiostrongylus) | ~2.4% | From Hawaiian cases. | [44] | |
Measles (rubeola), in developing countries | Virus (Measles morbillivirus) | Unvaccinated | ~ 1–3% | May reach 10–30% in some localities. | [14] |
Brucellosis | Bakteri (B. melitensis) | Belum ditemukan pengobatan khusus | ≤ 2% | [14] | |
Hepatitis A, adults > 50 years old | Virus (Hepatovirus A) | Unvaccinated | ~ 1.8% | [14] | |
Lassa fever | Virus (Lassa mammarenavirus) | ~ 1% | 15% in hospitalized patients; higher in some epidemics. | [14] | |
Mumps encephalitis | Virus (Mumps orthorubulavirus) | Unvaccinated | ~ 1% | [14] | |
Pertussis (batuk rejan), anak-anak di negara berkembang | Bakteri (Bordetella pertussis) | Unvaccinated | ~ 1% | For children 1–4 years old. | [14] |
Smallpox, Variola minor | Virus (Variola) | Unvaccinated | 1% | [10] | |
Venezuelan Equine Encephalitis (VEE) | Virus (Venezuelan equine encephalitis virus) | < 1% | [10] | ||
Anthrax, cutaneous | Bakteri (Bacillus anthracis) | < 1% | [10] | ||
Malaria | Parasit (Plasmodium) | ~ 0.3% | [45] | ||
Hepatitis A | Virus (Hepatovirus A) | Unvaccinated | 0.1–0.3% | [14] | |
Asian (1956–58) flu | Virus (Influenza) | ~ 0.1% | [46] | ||
Hong Kong (1968–69) flu | Virus (Influenza) | ~ 0.1% | [46] | ||
Influenza A, typical pandemics | Virus (Influenza) | < 0.1% | [43] | ||
Varicella (chickenpox), dewasa | Virus (Human alphaherpesvirus 3) | Unvaccinated | 0.02% | This is 1:5,000. | [14] |
Hand, foot and mouth disease, children < 5 years old | Virus (Picornaviridae) | 0.01% | This is 1:10,000. | [47] | |
Varicella (chickenpox), children | Virus (Human alphaherpesvirus 3) | Unvaccinated | 0.001% | This is 1:100,000. | [14] |
Lihat juga
- Lists of diseases
- List of infectious diseases
- List of causes of death by rate
- List of notifiable diseases – diseases that should be reported to public health officials
Referensi
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