Sefradin

Sefradin (INN) adalah antibiotik sefalosporin generasi pertama.

Sefradin

Nama sistematis (IUPAC)
(6R,7R)-7-{[(2R)-2-Amino-2-(1-sikloheksa-1,4-dienil)asetil]amino}-3-metil-8-okso-5-tia-1-azabisiklo[4.2.0]okt-2-ena-2-asam karboksilat
Data klinis
Nama dagang	Lihat teks
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601206
Kat. kehamilan	?
Status hukum	℞ Preskripsi saja
Rute	Oral, IM, IV
Data farmakokinetik
Bioavailabilitas	Diserap dengan baik
Ikatan protein	<10%
Metabolisme	Nol
Waktu paruh	0,9 jam
Ekskresi	Ginjal, tidak berubah
Pengenal
Nomor CAS	38821-53-3 Y
Kode ATC	J01DB09
PubChem	CID 38103
Ligan IUPHAR	4830
DrugBank	DB01333
ChemSpider	34933 Y
UNII	9YA6SX5S4D Y
KEGG	D00264 Y
ChEBI	CHEBI:3547 Y
ChEMBL	CHEMBL1604 Y
Data kimia
Rumus	C16H19N3O4S
SMILES	eMolecules & PubChem
InChI InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 Y Key:RDLPVSKMFDYCOR-UEKVPHQBSA-N Y
Data fisik
Titik lebur	140–142 °C (284–288 °F) (dec.)

Merek

Antibiotik ini diproduksi dengan banyak nama merek di seluruh dunia.

• Afrika Selatan: Cefril A
• Bangladesh: Ancef, Ancef forte, Aphrin, Avlosef, Cefadin, Cephadin, Cephran, Cephran-DS, Cusef, Cusef DS, Dicef , Dicef forte, Dolocef, Efrad, Elocef, Extracef, Extracef-DS, Intracef, Kefdrin, Lebac, Lebac Forte, Medicef, Mega-Cef, Megacin, Polycef, Procef, Procef, Procef forte, Rocef, Rocef Forte DS, Sefin, Sefin DS, Sefnin, Sefrad, Sefrad DS, Sefril, Sefril-DS, Sefro, Sefro-HS, Sephar, Sephar-DS, Septa, Sinaceph, SK-Cef, Sk-Cef DS, Supracef and Supracef-F, Torped, Ultrasef, Vecef, Vecef-DS, Velogen, Sinaceph, dan Velox
• Britania Raya: Cefradune (Kent)
• Cina: Cefradine, Cephradine, Kebili, Saifuding, Shen You, Taididing, Velosef, Xianyi, dan Xindadelei
• Filipina: Altozef, Racep, Senadex, Solphride, Yudinef, Zefadin, Zefradil, dan Zolicef
• Hong Kong: Cefradine dan ChinaQualisef-250
• Indonesia: Dynacef, Velodine, dan Velodrom
• Kolombia: Cefagram, Cefrakov, Cefranil , Cefrex, dan Kliacef
• Korea Selatan: Cefradine dan Tricef
• Lebanon: Eskacef, Julphacef, dan Velosef
• Lithuania: Tafril
• Mesir: Cefadrin dan Cefadrine, Cephradine, Cephraforte, Farcosef, Fortecef, Mepadrin, Ultracef, dan Velosef
• Myanmar: Sinaceph
• Oman: Ceframed, Eskasef, Omadine, dan Velocef
• Pakistan: Abidine, Ada-Cef, Ag-cef, Aksosef, Amspor, Anasef, Antimic, Atcosef, Bactocef, Biocef, Biodine, Velora, dan Velosef
• Peru: Abiocef, Cefradinal, Cefradur, Cefrid, Terbodina II, Velocef, dan Velomicin
• Polandia: Tafril
• Portugal: Cefalmin dan Cefradur
• Prancis: Dexef
• Taiwan: Cefadin, Cefamid, Cefin, Cekodin, Cephradine, Ceponin, Lacef, Licef-A, Lisacef, Lofadine, Recef, S-60, Sefree, Sephros, Topcef, Tydine, Unifradine, dan U-Save
• Vietnam: Eurosefro dan Incef