Metdilazin
senyawa kimia
Metdilazin adalah antihistamin generasi pertama dengan sifat antikolinergik dari kelas fenotiazin.
Nama sistematis (IUPAC) | |
---|---|
10-[(1-metilpirolidin-3-il) metil]- 10H-fenotiazina | |
Data klinis | |
AHFS/Drugs.com | monograph |
Kat. kehamilan | ? |
Status hukum | ? |
Pengenal | |
Nomor CAS | 1982-37-2 |
Kode ATC | R06AD04 |
PubChem | CID 14677 |
Ligan IUPHAR | 7231 |
DrugBank | DB00902 |
ChemSpider | 14009 |
UNII | 4Q13LY9Z8X |
KEGG | D04979 |
ChEBI | CHEBI:6823 |
ChEMBL | CHEMBL1200959 |
Data kimia | |
Rumus | C18H20N2S |
SMILES | eMolecules & PubChem |
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Sintesis
suntingReferensi
sunting- ^ L. W. Marsch and R. Peterson, Arzneimittel Forsch., 9, 715 (1959).
Bacaan lebih lanjut
sunting- Rani Basu L, Mazumdar K, Dutta N, Karak P, Dastidar S (2005). "Antibacterial property of the antipsychotic agent prochlorperazine, and its synergism with methdilazine". Microbiol Res. 160 (1): 95–100. doi:10.1016/j.micres.2004.10.002 . PMID 15782943.
- Chattopadhyay D, Mukherjee T, Pal P, Saha B, Bhadra R (1998). "Altered membrane permeability as the basis of bactericidal action of methdilazine". J Antimicrob Chemother. 42 (1): 83–6. doi:10.1093/jac/42.1.83 . PMID 9700532.
- Chattopadhyay D, Dastidar S, Chakrabarty A (1988). "Antimicrobial properties of methdilazine and its synergism with antibiotics and some chemotherapeutic agents". Arzneimittelforschung. 38 (7): 869–72. PMID 2905130.