Azatadin

Azatadin
Nama sistematis (IUPAC)
	11-(1-Metilpiperidin-4-ilidena)-6,11-dihidro-5H-benzo[5,6]siklohepta[1,2-b]piridina
Data klinis
Nama dagang	Optimine
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Kat. kehamilan	B(US)
Status hukum	?
Pengenal
Nomor CAS	3964-81-6
Kode ATC	R06AX09
PubChem	CID 19861
Ligan IUPHAR	7119
DrugBank	DB00719
ChemSpider	18709
UNII	94Z39NID6C
KEGG	D07482
ChEBI	CHEBI:2946
ChEMBL	CHEMBL946
Data kimia
Rumus	C20H22N2
SMILES	eMolecules & PubChem
	InChI InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3 ; Key:SEBMTIQKRHYNIT-UHFFFAOYSA-N ;

Azatadin adalah obat antihistamin dan antikolinergik generasi pertama yang disintesis pada tahun 1963 oleh Schering-Plough, bekas perusahaan farmasi Amerika Serikat.^[1]^[2]

Obat ini dipatenkan pada tahun 1967.^[3] Obat ini telah digantikan oleh loratadin dan desloratadin.^[4]^:53 dan persetujuan pemasarannya telah banyak ditarik.^[5]^[6]^[7]^[8]^:290^[9]

Referensi

^ Katelaris C (December 1990). "Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis". Asian Pacific Journal of Allergy and Immunology. 8 (2): 103–7. PMID 1982614.
^ Small P, Barrett D, Biskin N (February 1990). "Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation". Annals of Allergy. 64 (2 Pt 1): 129–31. PMID 1968324.
^ US 3326924, Villani FJ, Caldwell W, "Azatadine", dikeluarkan tanggal 1967
^ Horak F (2010). "Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4". Dalam Pawankar R, Holgate ST, Rosenwasser LJ. Allergy Frontiers:Therapy and Prevention. 5. Springer Science & Business Media. ISBN 9784431993629.
^ "Azatadine". Drugs.com.
^ Food and Drug Administration (2005). "Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications". Federal Register 70 FR 10651.
^ Food and Drug Administration (2007). "Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions". Federal Register 72 FR 8184.
^ "Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals" (PDF). Department of Economic and Social Affairs of the United Nations Secretariat. New York: United Nations. 2005.
^ "OGD Suitability Tracking Report (Sorted by Drug Name)". FDA.

[1] Katelaris C (December 1990). "Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis". Asian Pacific Journal of Allergy and Immunology. 8 (2): 103–7. PMID 1982614.

[2] Small P, Barrett D, Biskin N (February 1990). "Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation". Annals of Allergy. 64 (2 Pt 1): 129–31. PMID 1968324.

[3] US 3326924, Villani FJ, Caldwell W, "Azatadine", dikeluarkan tanggal 1967

[4] Horak F (2010). "Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4". Dalam Pawankar R, Holgate ST, Rosenwasser LJ. Allergy Frontiers:Therapy and Prevention. 5. Springer Science & Business Media. ISBN 9784431993629.

[5] "Azatadine". Drugs.com.

[6] Food and Drug Administration (2005). "Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications". Federal Register 70 FR 10651.

[7] Food and Drug Administration (2007). "Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions". Federal Register 72 FR 8184.

[8] "Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals" (PDF). Department of Economic and Social Affairs of the United Nations Secretariat. New York: United Nations. 2005.

[9] "OGD Suitability Tracking Report (Sorted by Drug Name)". FDA.

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